Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50030675
LigandPNGBDBM50299983((S)-1-(Methylsulfonylamino)-3-[3-(4-methoxyphenyl)...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299976(1-[(Methylsulfonyl)amino]-3-[(4-methoxyphenyl)ethy...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299977(1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)ethy...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299988(1-(Cyanomethylsulfonylamino)-3-[2-(4-methoxyphenyl...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299981(1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)ethy...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299975(1-(Methylsulfonylamino)-3-[(4-methoxyphenyl)ethyl]...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299978(1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)ethy...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299979((S)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299987(1-[(Phenylmethyl)sulfonylamino]-3-[2-(4-methoxyphe...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 480nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299986(1-(Methylsulfonylamino)-3-[2-(4-trifluoromethoxyph...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50198250(1-(2-(3,4-dimethylphenyl)thiazolidin-3-yl)-2-(4-me...)
Affinity DataIC50: 537nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299984((R)-1-(Methylsulfonylamino)-3-[3-(4-methoxyphenyl)...)
Affinity DataIC50: 560nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299990(1-[(Pyridin-3-yl)methylsulfonyl]amino-3-[2-(4-meth...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299974(1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)ethy...)
Affinity DataIC50: 610nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299985(1-(Methylsulfonylamino)-3-[2-(4-ethoxyphenyl)ethyl...)
Affinity DataIC50: 770nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299989(1-(Fluoromethylsulfonylamino)-3-[2-(4-methoxypheny...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of Kv1.3 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibition of Kv1.1 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of Kv4.3 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299987(1-[(Phenylmethyl)sulfonylamino]-3-[2-(4-methoxyphe...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299986(1-(Methylsulfonylamino)-3-[2-(4-trifluoromethoxyph...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299982(1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)ethy...)
Affinity DataIC50: 7.45E+3nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299976(1-[(Methylsulfonyl)amino]-3-[(4-methoxyphenyl)ethy...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299977(1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)ethy...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299978(1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)ethy...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299975(1-(Methylsulfonylamino)-3-[(4-methoxyphenyl)ethyl]...)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299985(1-(Methylsulfonylamino)-3-[2-(4-ethoxyphenyl)ethyl...)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299983((S)-1-(Methylsulfonylamino)-3-[3-(4-methoxyphenyl)...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299984((R)-1-(Methylsulfonylamino)-3-[3-(4-methoxyphenyl)...)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299974(1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)ethy...)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299981(1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)ethy...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 2.34E+4nMAssay Description:Inhibition of Cav1.3 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299979((S)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299989(1-(Fluoromethylsulfonylamino)-3-[2-(4-methoxypheny...)
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Nav1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Cav1.2 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299982(1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)ethy...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299988(1-(Cyanomethylsulfonylamino)-3-[2-(4-methoxyphenyl...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed