Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50031003
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305129(6-(2-aminoethoxy)-2-(4-phenoxyphenyl)-9,10-dihydro...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305140(7-(2-aminoethoxy)-2-(4-phenoxyphenyl)-9,10-dihydro...)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305119(7-(2-(dimethylamino)ethoxy)-2-(4-hydroxyphenyl)-9,...)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305131(6-(3-(dimethylamino)propoxy)-2-(4-phenoxyphenyl)-9...)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305139(6-(2-(4-methylpiperazin-1-yl)ethoxy)-2-(4-phenoxyp...)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305117(7-(2-morpholinoethoxy)-2-(4-phenoxyphenyl)-9,10-di...)
Affinity DataIC50: 0.560nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305126(7-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305126(7-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...)
Affinity DataIC50: 0.720nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305142(7-(2-hydroxyethoxy)-2-(4-phenoxyphenyl)-9,10-dihyd...)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305138(6-(2-morpholinoethoxy)-2-(4-phenoxyphenyl)-9,10-di...)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305121(7-(2-(dimethylamino)ethoxy)-2-(4-(phenylamino)phen...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305125(2-(4-(3-(2,6-dichlorophenyl)ureido)phenyl)-7-(2-(d...)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305135(2-(3-carbamoyl-2-(4-phenoxyphenyl)-9,10-dihydro-4H...)
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305141(7-(3-(dimethylamino)propoxy)-2-(4-phenoxyphenyl)-9...)
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305122(2-(4-(2,6-dichlorobenzylamino)phenyl)-7-(2-(dimeth...)
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305118(7-(2-(4-methylpiperazin-1-yl)ethoxy)-2-(4-phenoxyp...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305143(7-(2-amino-2-oxoethoxy)-2-(4-phenoxyphenyl)-9,10-d...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305130(6-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305132(6-(2-hydroxyethoxy)-2-(4-phenoxyphenyl)-9,10-dihyd...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305134(6-(2-amino-2-oxoethoxy)-2-(4-phenoxyphenyl)-9,10-d...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305126(7-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of CskMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305123(benzyl 4-(3-carbamoyl-7-(2-(dimethylamino)ethoxy)-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305124(7-(2-(dimethylamino)ethoxy)-2-(4-(3-phenylureido)p...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305128(7-methoxy-2-(4-phenoxyphenyl)-9,10-dihydro-4H-benz...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305145(2-(4-phenoxyphenyl)-7-(pyridin-3-ylmethoxy)-9,10-d...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305120(2-(4-aminophenyl)-7-(2-(dimethylamino)ethoxy)-9,10...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305136(6-(2-oxopropoxy)-2-(4-phenoxyphenyl)-9,10-dihydro-...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305127(6-methoxy-2-(4-phenoxyphenyl)-9,10-dihydro-4H-benz...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305144(2-(4-phenoxyphenyl)-7-(pyridin-2-ylmethoxy)-9,10-d...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305137(2-(4-phenoxyphenyl)-6-(pyridin-3-ylmethoxy)-9,10-d...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305116(2-(4-phenoxyphenyl)-7-(pyridin-4-ylmethoxy)-9,10-d...)
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305133(6-(4-methylpentyloxy)-2-(4-phenoxyphenyl)-9,10-dih...)
Affinity DataIC50: 100nMAssay Description:Inhibition of GST-tagged human LCK by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305126(7-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Zap70More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305126(7-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305126(7-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAPK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type IV(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305126(7-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CamK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305126(7-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305126(7-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKBalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305126(7-(2-(dimethylamino)ethoxy)-2-(4-phenoxyphenyl)-9,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed