Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50031010
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305271(5-[2-(4-Fluorophenyl)ethyl]-2,8-dimethyl-2,3,4,5-t...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305268(8-Fluoro-2-methyl-5-(2-p-tolylethyl)-2,3,4,5-tetra...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305266(8-Fluoro-5-[2-(4-methoxyphenyl)ethyl]-2-methyl-2,3...)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305260(2-Methyl-5-((Z)-styryl)-2,3,4,5-tetrahydro-1H-pyri...)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305267(8-Fluoro-2-methyl-5-[2-(4-trifluoromethylphenyl)et...)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305263(2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyr...)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305262(8-Fluoro-2-methyl-5-phenethyl-2,3,4,5-tetrahydro-1...)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305269(5-[2-(4-Methoxyphenyl)ethyl]-2,8-dimethyl-2,3,4,5-...)
Affinity DataIC50: 66nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305265(2-Methyl-5-phenethyl-8-trifluoromethyl-2,3,4,5-tet...)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305258(2,8-Dimethyl-5-((Z)-styryl)-2,3,4,5-tetrahydro-1H-...)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305258(2,8-Dimethyl-5-((Z)-styryl)-2,3,4,5-tetrahydro-1H-...)
Affinity DataIC50: 87nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305270(2,8-Dimethyl-5-[2-(4-trifluoromethylphenyl)ethyl]-...)
Affinity DataIC50: 98nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305264(8-Methoxy-2-methyl-5-phenethyl-2,3,4,5-tetrahydro-...)
Affinity DataIC50: 104nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305272(2,8-Dimethyl-5-(2-p-tolylethyl)-2,3,4,5-tetrahydro...)
Affinity DataIC50: 112nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305262(8-Fluoro-2-methyl-5-phenethyl-2,3,4,5-tetrahydro-1...)
Affinity DataIC50: 131nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as reduction of histamine-induced intracellular calcium spike at phase 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305263(2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyr...)
Affinity DataIC50: 146nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as reduction of histamine-induced intracellular calcium spike at phase 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305258(2,8-Dimethyl-5-((Z)-styryl)-2,3,4,5-tetrahydro-1H-...)
Affinity DataIC50: 154nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as reduction of histamine-induced intracellular calcium spike at phase 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305261(Dimebolin | CHEMBL589390)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305263(2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyr...)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305255(25-[(Z)-2-(4-Fluorophenyl)vinyl]-2,8-dimethyl-2,3,...)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305260(2-Methyl-5-((Z)-styryl)-2,3,4,5-tetrahydro-1H-pyri...)
Affinity DataIC50: 181nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as reduction of histamine-induced intracellular calcium spike at phase 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305272(2,8-Dimethyl-5-(2-p-tolylethyl)-2,3,4,5-tetrahydro...)
Affinity DataIC50: 276nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305259(2-Methyl-5-((E)-styryl)-2,3,4,5-tetrahydro-1H-pyri...)
Affinity DataIC50: 345nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305253(5-[(Z)-2-(4-Methoxyphenyl)vinyl]-2,8-dimethyl-2,3,...)
Affinity DataIC50: 550nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305269(5-[2-(4-Methoxyphenyl)ethyl]-2,8-dimethyl-2,3,4,5-...)
Affinity DataIC50: 666nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305262(8-Fluoro-2-methyl-5-phenethyl-2,3,4,5-tetrahydro-1...)
Affinity DataIC50: 692nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305256(2,8-Dimethyl-5-((Z)-2-p-tolylvinyl)-2,3,4,5-tetrah...)
Affinity DataIC50: 910nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305265(2-Methyl-5-phenethyl-8-trifluoromethyl-2,3,4,5-tet...)
Affinity DataIC50: 974nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305271(5-[2-(4-Fluorophenyl)ethyl]-2,8-dimethyl-2,3,4,5-t...)
Affinity DataIC50: 977nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305252(8-Fluoro-2-methyl-5-((Z)-styryl)-2,3,4,5-tetrahydr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305264(8-Methoxy-2-methyl-5-phenethyl-2,3,4,5-tetrahydro-...)
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305273(8-Fluoro-5-[2-(4-fluorophenyl)ethyl]-2-methyl-2,3,...)
Affinity DataIC50: 1.13E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305261(Dimebolin | CHEMBL589390)
Affinity DataIC50: 1.16E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305249(8-Fluoro-2-methyl-5-((Z)-2-p-tolylvinyl)-2,3,4,5-t...)
Affinity DataIC50: 1.44E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305276(8-Fluoro-5-[(Z)-2-(4-methoxyphenyl)-vinyl]-2-methy...)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305261(Dimebolin | CHEMBL589390)
Affinity DataIC50: 1.58E+3nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as reduction of histamine-induced intracellular calcium spike at phase 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305257(2,8-Dimethyl-5-((E)-styryl)-2,3,4,5-tetrahydro-1H-...)
Affinity DataIC50: 1.68E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305250(8-Fluoro-2-methyl-5-((E)-styryl)-2,3,4,5-tetrahydr...)
Affinity DataIC50: 1.75E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305275(8-Methyl-5-[(Z)-1-methyl-2-phenylvinyl]-2-methyl-2...)
Affinity DataIC50: 1.98E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305259(2-Methyl-5-((E)-styryl)-2,3,4,5-tetrahydro-1H-pyri...)
Affinity DataIC50: 2.13E+3nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as reduction of histamine-induced intracellular calcium spike at phase 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305268(8-Fluoro-2-methyl-5-(2-p-tolylethyl)-2,3,4,5-tetra...)
Affinity DataIC50: 2.27E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305266(8-Fluoro-5-[2-(4-methoxyphenyl)ethyl]-2-methyl-2,3...)
Affinity DataIC50: 2.35E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305259(2-Methyl-5-((E)-styryl)-2,3,4,5-tetrahydro-1H-pyri...)
Affinity DataIC50: 2.58E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305254(2,8-Dimethyl-5-[(Z)-2-(4-trifluoromethylphenyl)vin...)
Affinity DataIC50: 2.81E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305251(8-Fluoro-5-[(Z)-2-(4-fluorophenyl)-vinyl]-2-methyl...)
Affinity DataIC50: 2.95E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305274(8-Fluoro-5-[(Z)-1-methyl-2-phenylvinyl]-2-methyl-2...)
Affinity DataIC50: 3.72E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305270(2,8-Dimethyl-5-[2-(4-trifluoromethylphenyl)ethyl]-...)
Affinity DataIC50: 4.07E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305277(8-Fluoro-2-methyl-5-[(Z)-2-(4-trifluoromethyl-phen...)
Affinity DataIC50: 5.58E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305260(2-Methyl-5-((Z)-styryl)-2,3,4,5-tetrahydro-1H-pyri...)
Affinity DataIC50: 5.73E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305267(8-Fluoro-2-methyl-5-[2-(4-trifluoromethylphenyl)et...)
Affinity DataIC50: 2.07E+4nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed