Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50000925
TargetThymidylate synthase(Human)
Parke-Davis Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50008294(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataKi:  4.5nMAssay Description:Binding affinity against thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Parke-Davis Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50011243(CHEMBL171480 | 2-{4-[(4-Oxo-3,4-dihydro-quinazolin...)
Affinity DataKi:  26nMAssay Description:Binding affinity against thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Parke-Davis Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50011244(CHEMBL417222 | 6-{[(4-Benzenesulfonyl-phenyl)-prop...)
Affinity DataKi:  27nMAssay Description:Binding affinity against thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Parke-Davis Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50011243(CHEMBL171480 | 2-{4-[(4-Oxo-3,4-dihydro-quinazolin...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed