Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50031036
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305692(CHEMBL1198626 | CHEMBL609275 | 3-tert-butyl-6-(2,4...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305696(3-(2,4-difluorophenyl)-6-(2,4-difluorophenylthio)-...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305704(methyl 3-(6-(2,4-difluorophenylthio)-[1,2,4]triazo...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305720(5-chloro-6-(2,4-difluorophenylthio)-3-isopropyl-[1...)
Affinity DataIC50: 12.3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305694(6-(2,4-difluorophenylthio)-3-(2-methylpent-4-en-2-...)
Affinity DataIC50: 16.3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305709(3-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-...)
Affinity DataIC50: 20.5nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305693(6-(2,4-difluorophenylthio)-3-(1-methylcyclopropyl)...)
Affinity DataIC50: 24.9nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305729(6-(2,4-difluorobenzyl)-3-isopropyl-1,8a-dihydro-[1...)
Affinity DataIC50: 26.1nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305699(1-(4-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4...)
Affinity DataIC50: 28.3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305700(2-(4-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4...)
Affinity DataIC50: 33.3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305707(3-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-...)
Affinity DataIC50: 39.9nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305708(N-(2-amino-2-oxoethyl)-3-(6-(2,4-difluorophenylthi...)
Affinity DataIC50: 46.5nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305706(3-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-...)
Affinity DataIC50: 60.8nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305691(6-(2,4-difluorophenylthio)-3-isopropyl-[1,2,4]tria...)
Affinity DataIC50: 79.3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305730(6-(2,4-difluorophenethyl)-3-isopropyl-1,8a-dihydro...)
Affinity DataIC50: 85nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305698(6-(2,4-difluorophenylthio)-3-(2-methyl-4-vinylphen...)
Affinity DataIC50: 106nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305697(3-(4-bromo-2-methylphenyl)-6-(2,4-difluorophenylth...)
Affinity DataIC50: 141nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305701(methyl 3-(6-(2,4-difluorophenylthio)-[1,2,4]triazo...)
Affinity DataIC50: 181nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305712(4-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-...)
Affinity DataIC50: 201nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305716(1-(4-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4...)
Affinity DataIC50: 212nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305703(3-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-...)
Affinity DataIC50: 241nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305713(4-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-...)
Affinity DataIC50: 293nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305710(methyl 4-(6-(2,4-difluorophenylthio)-[1,2,4]triazo...)
Affinity DataIC50: 322nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305715(2-(4-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4...)
Affinity DataIC50: 367nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305721(7-chloro-6-(2,4-difluorophenylthio)-3-isopropyl-[1...)
Affinity DataIC50: 889nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305724((2,4-difluorophenyl)(3-isopropyl-[1,2,4]triazolo[4...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305711(4-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-...)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305695(4-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-...)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305705(3-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-...)
Affinity DataIC50: 2.92E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305722(5,7-dichloro-6-(2,4-difluorophenylthio)-3-isopropy...)
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305714(6-(2,4-difluorophenylthio)-3-(piperidin-4-yl)-[1,2...)
Affinity DataIC50: 3.77E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305723(5-bromo-7-chloro-6-(2,4-difluorophenylthio)-3-isop...)
Affinity DataIC50: 6.08E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305728(2-(3,5-difluorophenyl)-1-(3-isopropyl-[1,2,4]triaz...)
Affinity DataIC50: 7.37E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305702(3-(6-(2,4-difluorophenylthio)-[1,2,4]triazolo[4,3-...)
Affinity DataIC50: 7.42E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305719(6-(2,4-dichlorophenylthio)-3-isopropyl-[1,2,4]tria...)
Affinity DataIC50: 8.24E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305725(6-(2,4-difluorophenylsulfinyl)-3-isopropyl-[1,2,4]...)
Affinity DataIC50: 9.68E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305718(6-(4-fluoro-2-(trifluoromethyl)phenylthio)-3-isopr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305717(6-(4-bromo-2-(trifluoromethyl)phenylthio)-3-isopro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305726(6-(2,4-difluorophenylsulfonyl)-3-isopropyl-[1,2,4]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305727(N-(3,5-difluorophenyl)-3-isopropyl-[1,2,4]triazolo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed