Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50038956
TargetGlycogen synthase kinase-3 beta(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM8296(CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50300206(5-Ethyl-7,8-dimethoxy-1H-benzo[e]isoindole-1,3(2H)...)
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM8296(CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...)
Affinity DataIC50: 269nMAssay Description:Inhibition of human CDK2/Cyclin A by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50300205(7,8-Dimethoxy-5-methyl-1H-benzo[e]isoindole-1,3(2H...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50300207(Methyl 4-Isobutyl-1,3-dioxo-2,3-dihydro-1H-benzo[e...)
Affinity DataIC50: 486nMAssay Description:Inhibition of human recombinant GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50300205(7,8-Dimethoxy-5-methyl-1H-benzo[e]isoindole-1,3(2H...)
Affinity DataIC50: 787nMAssay Description:Inhibition of human CDK2/Cyclin A by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50300205(7,8-Dimethoxy-5-methyl-1H-benzo[e]isoindole-1,3(2H...)
Affinity DataKi:  259nMAssay Description:Inhibition of human recombinant GSK3-beta at 1 uM by ATP competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed