Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50031241
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309621(3-((5'-chloro-3,3'-difluoro-2'-(2-methyl-2H-tetraz...)
Affinity DataIC50: 0.190nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309622(3-((5'-chloro-3,3'-difluoro-2'-(2-methyl-2H-tetraz...)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309619(3-((5'-chloro-3,3'-difluoro-2'-(2-methyl-2H-tetraz...)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309617(3-((5'-chloro-3,3'-difluoro-2'-(2-methyl-2H-tetraz...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309607((R)-3-(1-(5-(5-chloro-3-fluoro-2-(5-methyl-1,2,4-o...)
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309618(1-tert-butyl-3-((5'-chloro-3,3'-difluoro-2'-(2-met...)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309609((R)-3-(1-(5-(3,5-dichloro-2-(5-methyl-1,2,4-oxadia...)
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309611((R)-3-(1-(5-(5-chloro-3-fluoro-2-(5-methyl-1,2,4-o...)
Affinity DataIC50: 3.60nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309620(3-((5'-chloro-3,3'-difluoro-2'-(2-methyl-2H-tetraz...)
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309616(3-((5'-chloro-3,3'-difluoro-2'-(2-methyl-2H-tetraz...)
Affinity DataIC50: 4.60nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309615(3-((5'-chloro-3,3'-difluoro-2'-(2-methyl-2H-tetraz...)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309608(3-((5-(5-chloro-3-fluoro-2-(5-methyl-1,2,4-oxadiaz...)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309610((R)-3-(1-(3-fluoro-5-(3-fluoro-2-(5-methyl-1,2,4-o...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309612(3-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-oxa...)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309614(1-((5'-chloro-3,3'-difluoro-2'-(2-methyl-2H-tetraz...)
Affinity DataIC50: 59nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309613(3-((5'-chloro-3'-fluoro-2'-(5-methyl-1,2,4-oxadiaz...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells assessed as inhibition of des-Arg-bradykinin-mediated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed