Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50031248
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309833((S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-car...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50216689(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50: 3.54E+3nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309832(2H-chromeno[2,3-d]pyrimidine-2,4(3H)-dione | CHEMB...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309831(10-Phenyl-7-oxa-8,10-diaza-benzo[a]anthracene-9,11...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309830(2-(2-chlorobenzoyl)-1H-benzo[f]chromen-3(2H)-one |...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309833((S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-car...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309829(1-((3-(2-phenylpropylthio)phenylimino)methyl)napht...)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309828((E)-4-((2-hydroxynaphthalen-1-yl)methyleneamino)-N...)
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309827(Salermide | CHEMBL597845)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50177984(para-Sirtinol | CHEMBL372375)
Affinity DataIC50: 2.99E+4nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50177985(meta-Sirtinol | CHEMBL200762)
Affinity DataIC50: 3.45E+4nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309829(1-((3-(2-phenylpropylthio)phenylimino)methyl)napht...)
Affinity DataIC50: 4.03E+4nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309827(Salermide | CHEMBL597845)
Affinity DataIC50: 4.28E+4nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309828((E)-4-((2-hydroxynaphthalen-1-yl)methyleneamino)-N...)
Affinity DataIC50: 4.41E+4nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50156760(2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...)
Affinity DataIC50: 4.59E+4nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50177984(para-Sirtinol | CHEMBL372375)
Affinity DataIC50: 4.81E+4nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50216689(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50177985(meta-Sirtinol | CHEMBL200762)
Affinity DataIC50: 5.86E+4nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309830(2-(2-chlorobenzoyl)-1H-benzo[f]chromen-3(2H)-one |...)
Affinity DataIC50: 8.98E+4nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM29590(1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one | CHEMBL8...)
Affinity DataIC50: 9.62E+4nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM29590(1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one | CHEMBL8...)
Affinity DataIC50: 1.13E+5nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50156760(2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...)
Affinity DataIC50: 1.23E+5nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309831(10-Phenyl-7-oxa-8,10-diaza-benzo[a]anthracene-9,11...)
Affinity DataIC50: 1.91E+5nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309832(2H-chromeno[2,3-d]pyrimidine-2,4(3H)-dione | CHEMB...)
Affinity DataIC50: 2.44E+5nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed