Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50031265
TargetMitogen-activated protein kinase 9(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310146(N-(3,4-Dimethoxyphenethyl)-5-(5-nitrothiazol-2-ylt...)
Affinity DataIC50: 100nMAssay Description:Displacement of biotin-labeled pep-JIP1from JNK2 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310143(N-(4-Methoxybenzyl)-5-(5-nitrothiazol-2-ylthio)-1,...)
Affinity DataIC50: 100nMAssay Description:Displacement of biotin-labeled pep-JIP1from JNK2 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310147(BI-98A10 | N-sec-Butyl-5-(5-nitrothiazol-2-ylthio)...)
Affinity DataIC50: 140nMAssay Description:Displacement of biotin-labeled pep-JIP1from JNK2 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | N-(2-Methoxyethyl)-5-(5-nitrothiazol-2-y...)
Affinity DataIC50: 160nMAssay Description:Displacement of biotin-labeled pep-JIP1from JNK2 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM26057(4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(5-nitro-1...)
Affinity DataIC50: 280nMAssay Description:Inhibition of JNK1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310142(BI-90H6 | 5-(5-Nitrothiazol-2-ylthio)-N-propyl-1,3...)
Affinity DataIC50: 290nMAssay Description:Displacement of biotin-labeled pep-JIP1from JNK2 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310144(BI-90H5 | 5-(5-Nitrothiazol-2-ylthio)-N-((tetrahyd...)
Affinity DataIC50: 470nMAssay Description:Displacement of biotin-labeled pep-JIP1from JNK2 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM26057(4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(5-nitro-1...)
Affinity DataIC50: 500nMAssay Description:Displacement of biotin-labeled pep-JIP1from JNK2 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | N-(2-Methoxyethyl)-5-(5-nitrothiazol-2-y...)
Affinity DataKd:  2.80E+3nMAssay Description:Inhibition of wild-type JNK2 by isothermal calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310147(BI-98A10 | N-sec-Butyl-5-(5-nitrothiazol-2-ylthio)...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of JNK1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | N-(2-Methoxyethyl)-5-(5-nitrothiazol-2-y...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of JNK1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310146(N-(3,4-Dimethoxyphenethyl)-5-(5-nitrothiazol-2-ylt...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of JNK1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310142(BI-90H6 | 5-(5-Nitrothiazol-2-ylthio)-N-propyl-1,3...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of JNK1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM26057(4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[(5-nitro-1...)
Affinity DataKd:  8.10E+3nMAssay Description:Inhibition of wild-type JNK2 by isothermal calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310143(N-(4-Methoxybenzyl)-5-(5-nitrothiazol-2-ylthio)-1,...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of JNK1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310142(BI-90H6 | 5-(5-Nitrothiazol-2-ylthio)-N-propyl-1,3...)
Affinity DataKd:  9.40E+3nMAssay Description:Inhibition of wild-type JNK2 by isothermal calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310145(N-Ethyl-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiaz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of biotin-labeled pep-JIP1from JNK2 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310144(BI-90H5 | 5-(5-Nitrothiazol-2-ylthio)-N-((tetrahyd...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFurin(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310147(BI-98A10 | N-sec-Butyl-5-(5-nitrothiazol-2-ylthio)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FURINMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFurin(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310146(N-(3,4-Dimethoxyphenethyl)-5-(5-nitrothiazol-2-ylt...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FURINMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFurin(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | N-(2-Methoxyethyl)-5-(5-nitrothiazol-2-y...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FURINMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFurin(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310142(BI-90H6 | 5-(5-Nitrothiazol-2-ylthio)-N-propyl-1,3...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FURINMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | N-(2-Methoxyethyl)-5-(5-nitrothiazol-2-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310142(BI-90H6 | 5-(5-Nitrothiazol-2-ylthio)-N-propyl-1,3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | N-(2-Methoxyethyl)-5-(5-nitrothiazol-2-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310142(BI-90H6 | 5-(5-Nitrothiazol-2-ylthio)-N-propyl-1,3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310147(BI-98A10 | N-sec-Butyl-5-(5-nitrothiazol-2-ylthio)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310146(N-(3,4-Dimethoxyphenethyl)-5-(5-nitrothiazol-2-ylt...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310147(BI-98A10 | N-sec-Butyl-5-(5-nitrothiazol-2-ylthio)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310146(N-(3,4-Dimethoxyphenethyl)-5-(5-nitrothiazol-2-ylt...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310148(BI-90H9 | N-(2-Methoxyethyl)-5-(5-nitrothiazol-2-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacillus anthracis anthrax lethal factorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310142(BI-90H6 | 5-(5-Nitrothiazol-2-ylthio)-N-propyl-1,3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacillus anthracis anthrax lethal factorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310147(BI-98A10 | N-sec-Butyl-5-(5-nitrothiazol-2-ylthio)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacillus anthracis anthrax lethal factorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310146(N-(3,4-Dimethoxyphenethyl)-5-(5-nitrothiazol-2-ylt...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bacillus anthracis anthrax lethal factorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50310145(N-Ethyl-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiaz...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of JNK1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed