Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50031621
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316344(2-(5-{[(2R)-2-Aminopropyl]oxy}pyridin-3-yl)-8,9-di...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316346(2-(5-{[(2R)-2-Aminobutyl]oxy}pyridin-3-yl)-8,9-dim...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316351(2-(5-{[(2S)-2-Amino-3-(4-fluorophenyl)propyl]oxy}p...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316342(2-[5-(2-Aminoethoxy)pyridin-3-yl]-8,9-dimethoxyben...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316343(2-(5-{[(2S)-2-Aminopropyl]oxy}pyridin-3-yl)-8,9-di...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316345(2-(5-{[(2S)-2-Aminobutyl]oxy}pyridin-3-yl)-8,9-dim...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316359(2-(5-{[(2S)-2-Amino-3-(3,4-dichlorophenyl)propyl]o...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316355(2-(5-{[(2S)-2-Amino-3-(1H-indol-3-yl)propyl]oxy}py...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316358(2-(5-{[(2S)-2-Amino-3-(3-chlorophenyl)propyl]oxy}p...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316357(2-(5-{[(2S)-2-Amino-3-(2-chlorophenyl)propyl]oxy}p...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316349(2-(5-{[(2S)-2-Amino-3-phenylpropyl]oxy}pyridin-3-y...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316360(2-(5-{[(2S)-2-Amino-3-pyridin-4-ylpropyl]oxy}pyrid...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316353(2-[5-({(2S)-2-Amino-3-[3-(trifluoromethyl)phenyl]p...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316347(2-(5-{[(2S)-2-Amino-4-methylpentyl]oxy}pyridin-3-y...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316352(2-(5-{[(2R)-2-Amino-3-(4-fluorophenyl)propyl]oxy}p...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316356(2-(5-{[(2R)-2-Amino-3-(1H-indol-3-yl)propyl]oxy}py...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316350(2-(5-{[(2R)-2-amino-3-phenylpropyl]oxy}pyridin-3-y...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316348(2-(5-{[(2R)-2-Amino-4-methylpentyl]oxy}pyridin-3-y...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316359(2-(5-{[(2S)-2-Amino-3-(3,4-dichlorophenyl)propyl]o...)
Affinity DataIC50: 19nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316354(2-[5-({(2R)-2-Amino-3-[3-(trifluoromethyl)phenyl]p...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316351(2-(5-{[(2S)-2-Amino-3-(4-fluorophenyl)propyl]oxy}p...)
Affinity DataIC50: 21nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM19087(15,16-dimethoxy-6-methyl-8,12-diazatetracyclo[8.8....)
Affinity DataIC50: 60nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316346(2-(5-{[(2R)-2-Aminobutyl]oxy}pyridin-3-yl)-8,9-dim...)
Affinity DataIC50: 72nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316358(2-(5-{[(2S)-2-Amino-3-(3-chlorophenyl)propyl]oxy}p...)
Affinity DataIC50: 76nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316355(2-(5-{[(2S)-2-Amino-3-(1H-indol-3-yl)propyl]oxy}py...)
Affinity DataIC50: 77nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316358(2-(5-{[(2S)-2-Amino-3-(3-chlorophenyl)propyl]oxy}p...)
Affinity DataIC50: 78nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316342(2-[5-(2-Aminoethoxy)pyridin-3-yl]-8,9-dimethoxyben...)
Affinity DataIC50: 80nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316350(2-(5-{[(2R)-2-amino-3-phenylpropyl]oxy}pyridin-3-y...)
Affinity DataIC50: 88nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316352(2-(5-{[(2R)-2-Amino-3-(4-fluorophenyl)propyl]oxy}p...)
Affinity DataIC50: 93nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316344(2-(5-{[(2R)-2-Aminopropyl]oxy}pyridin-3-yl)-8,9-di...)
Affinity DataIC50: 97nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316357(2-(5-{[(2S)-2-Amino-3-(2-chlorophenyl)propyl]oxy}p...)
Affinity DataIC50: 106nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316349(2-(5-{[(2S)-2-Amino-3-phenylpropyl]oxy}pyridin-3-y...)
Affinity DataIC50: 107nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316353(2-[5-({(2S)-2-Amino-3-[3-(trifluoromethyl)phenyl]p...)
Affinity DataIC50: 182nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316351(2-(5-{[(2S)-2-Amino-3-(4-fluorophenyl)propyl]oxy}p...)
Affinity DataIC50: 183nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316353(2-[5-({(2S)-2-Amino-3-[3-(trifluoromethyl)phenyl]p...)
Affinity DataIC50: 209nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316345(2-(5-{[(2S)-2-Aminobutyl]oxy}pyridin-3-yl)-8,9-dim...)
Affinity DataIC50: 216nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316347(2-(5-{[(2S)-2-Amino-4-methylpentyl]oxy}pyridin-3-y...)
Affinity DataIC50: 219nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316343(2-(5-{[(2S)-2-Aminopropyl]oxy}pyridin-3-yl)-8,9-di...)
Affinity DataIC50: 235nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316352(2-(5-{[(2R)-2-Amino-3-(4-fluorophenyl)propyl]oxy}p...)
Affinity DataIC50: 251nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316356(2-(5-{[(2R)-2-Amino-3-(1H-indol-3-yl)propyl]oxy}py...)
Affinity DataIC50: 254nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316350(2-(5-{[(2R)-2-amino-3-phenylpropyl]oxy}pyridin-3-y...)
Affinity DataIC50: 259nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316349(2-(5-{[(2S)-2-Amino-3-phenylpropyl]oxy}pyridin-3-y...)
Affinity DataIC50: 261nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316355(2-(5-{[(2S)-2-Amino-3-(1H-indol-3-yl)propyl]oxy}py...)
Affinity DataIC50: 302nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316346(2-(5-{[(2R)-2-Aminobutyl]oxy}pyridin-3-yl)-8,9-dim...)
Affinity DataIC50: 318nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316360(2-(5-{[(2S)-2-Amino-3-pyridin-4-ylpropyl]oxy}pyrid...)
Affinity DataIC50: 343nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316344(2-(5-{[(2R)-2-Aminopropyl]oxy}pyridin-3-yl)-8,9-di...)
Affinity DataIC50: 377nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316342(2-[5-(2-Aminoethoxy)pyridin-3-yl]-8,9-dimethoxyben...)
Affinity DataIC50: 402nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316345(2-(5-{[(2S)-2-Aminobutyl]oxy}pyridin-3-yl)-8,9-dim...)
Affinity DataIC50: 422nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316359(2-(5-{[(2S)-2-Amino-3-(3,4-dichlorophenyl)propyl]o...)
Affinity DataIC50: 433nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316348(2-(5-{[(2R)-2-Amino-4-methylpentyl]oxy}pyridin-3-y...)
Affinity DataIC50: 443nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
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