Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50031429
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313143(5-fluoro-3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-...)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313130(3-(phenylsulfonyl)-1-(piperidin-3-yl)-1H-indole | ...)
Affinity DataEC50:  82nMAssay Description:Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313131(1-(1-ethylpiperidin-3-yl)-3-(phenylsulfonyl)-1H-in...)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313132(3-(3-fluorophenylsulfonyl)-1-(piperidin-3-yl)-1H-i...)
Affinity DataEC50:  56nMAssay Description:Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313133(3-(3-fluorophenylsulfonyl)-5-methoxy-1-(piperidin-...)
Affinity DataEC50:  73nMAssay Description:Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313135(1-(1-ethylpiperidin-3-yl)-3-(3-fluorophenylsulfony...)
Affinity DataEC50:  203nMAssay Description:Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313137(8-(1-(piperidin-3-yl)-1H-indol-3-ylsulfonyl)quinol...)
Affinity DataEC50:  592nMAssay Description:Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313139(3-(phenylsulfonyl)-1-(pyrrolidin-3-yl)-1H-indole |...)
Affinity DataEC50:  60nMAssay Description:Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313140(3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-3-yl)-1H-...)
Affinity DataEC50:  68nMAssay Description:Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313141(3-(3-fluorophenylsulfonyl)-1-(1-methylpyrrolidin-3...)
Affinity DataEC50:  398nMAssay Description:Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313147(3-(3-chlorophenylsulfonyl)-1-(pyrrolidin-3-yl)-1H-...)
Affinity DataEC50:  125nMAssay Description:Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313121(3-(3-chlorophenylsulfonyl)-1-(1-methylpyrrolidin-3...)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313118(5-fluoro-3-(3-fluorophenylsulfonyl)-1-(piperidin-3...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313124(1-(1-methylpyrrolidin-3-yl)-3-(naphthalen-1-ylsulf...)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313126(8-(1-(1-methylpyrrolidin-3-yl)-1H-indol-3-ylsulfon...)
Affinity DataIC50: 76nMAssay Description:Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313122(3-(3-chlorophenylsulfonyl)-6-methoxy-1-(pyrrolidin...)
Affinity DataIC50: 80nMAssay Description:Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313125(8-(1-(pyrrolidin-3-yl)-1H-indol-3-ylsulfonyl)quino...)
Affinity DataIC50: 82nMAssay Description:Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313120(5-fluoro-3-(3-fluorophenylsulfonyl)-1-(1-methylpyr...)
Affinity DataIC50: 94nMAssay Description:Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313119(1-(1-methylpiperidin-3-yl)-3-(naphthalen-1-ylsulfo...)
Affinity DataIC50: 107nMAssay Description:Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313123(3-(naphthalen-1-ylsulfonyl)-1-(pyrrolidin-3-yl)-1H...)
Affinity DataIC50: 107nMAssay Description:Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313121(3-(3-chlorophenylsulfonyl)-1-(1-methylpyrrolidin-3...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313125(8-(1-(pyrrolidin-3-yl)-1H-indol-3-ylsulfonyl)quino...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313126(8-(1-(1-methylpyrrolidin-3-yl)-1H-indol-3-ylsulfon...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313147(3-(3-chlorophenylsulfonyl)-1-(pyrrolidin-3-yl)-1H-...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313141(3-(3-fluorophenylsulfonyl)-1-(1-methylpyrrolidin-3...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313118(5-fluoro-3-(3-fluorophenylsulfonyl)-1-(piperidin-3...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313122(3-(3-chlorophenylsulfonyl)-6-methoxy-1-(pyrrolidin...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313140(3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-3-yl)-1H-...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313120(5-fluoro-3-(3-fluorophenylsulfonyl)-1-(1-methylpyr...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313139(3-(phenylsulfonyl)-1-(pyrrolidin-3-yl)-1H-indole |...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313137(8-(1-(piperidin-3-yl)-1H-indol-3-ylsulfonyl)quinol...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313132(3-(3-fluorophenylsulfonyl)-1-(piperidin-3-yl)-1H-i...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313124(1-(1-methylpyrrolidin-3-yl)-3-(naphthalen-1-ylsulf...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313119(1-(1-methylpiperidin-3-yl)-3-(naphthalen-1-ylsulfo...)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313131(1-(1-ethylpiperidin-3-yl)-3-(phenylsulfonyl)-1H-in...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313143(5-fluoro-3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-...)
Affinity DataKi:  9.60nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313133(3-(3-fluorophenylsulfonyl)-5-methoxy-1-(piperidin-...)
Affinity DataKi:  10.7nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313130(3-(phenylsulfonyl)-1-(piperidin-3-yl)-1H-indole | ...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313145(5-chloro-3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313135(1-(1-ethylpiperidin-3-yl)-3-(3-fluorophenylsulfony...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313142(4-fluoro-3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313144(6-fluoro-3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313136(3-(naphthalen-1-ylsulfonyl)-1-(piperidin-3-yl)-1H-...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313123(3-(naphthalen-1-ylsulfonyl)-1-(pyrrolidin-3-yl)-1H...)
Affinity DataKi:  23.3nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313127(1-(1-benzylpiperidin-4-yl)-3-(phenylsulfonyl)-1H-i...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313134(3-(3-fluorophenylsulfonyl)-5-methoxy-1-(1-methylpi...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313146(6-chloro-3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313128(3-(phenylsulfonyl)-1-(piperidin-4-yl)-1H-indole | ...)
Affinity DataKi:  91nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313138(1-(1-benzylpyrrolidin-3-yl)-3-(phenylsulfonyl)-1H-...)
Affinity DataKi:  113nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313129(1-(1-benzylpiperidin-3-yl)-3-(phenylsulfonyl)-1H-i...)
Affinity DataKi:  122nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed