Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50031122
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307501((6S)-N,N-dipropyl-5,6,7,8-tetrahydro-1,1'-binaphth...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50139351(2-(6-cyclohexylpyridin-2-ylthio)-N,N-dimethylethan...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50150684([(R)-8-(2,6-Dimethoxy-phenyl)-chroman-3-yl]-dimeth...)
Affinity DataKi:  2.55nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50150685(((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...)
Affinity DataKi:  2.91nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50150676((R)-8-phenyl-N,N-dipropylchroman-3-amine | ((R)-8-...)
Affinity DataKi:  3.38nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50139355(Dimethyl-[2-(6-phenyl-pyridin-2-ylsulfanyl)-ethyl]...)
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50210123(N,N-dimethyl-2-(2'-methylbiphenyl-3-yl)ethanamine ...)
Affinity DataKi:  7.60nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50139357(Dimethyl-[2-(4-phenyl-thiazol-2-ylsulfanyl)-ethyl]...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50160366([(S)-6-(2,6-Dimethyl-phenyl)-chroman-3-yl]-dimethy...)
Affinity DataKi:  13.4nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307490(2-(6-(Furan-3-yl)pyridin-2-yloxy)-N,N-dimethyl-eth...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307490(2-(6-(Furan-3-yl)pyridin-2-yloxy)-N,N-dimethyl-eth...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50139361(2-(6-Bromopyridin-2-ylthio)-N,N-dimethylethanamine...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50139355(Dimethyl-[2-(6-phenyl-pyridin-2-ylsulfanyl)-ethyl]...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307488(2-(6-(2,6-Dimethylphenyl)pyridin-2-ylthio)-N,Ndime...)
Affinity DataKi:  128nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50139361(2-(6-Bromopyridin-2-ylthio)-N,N-dimethylethanamine...)
Affinity DataKi:  133nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307494(2-(Biphenyl-2-yloxy)-N,N-dimethylethanamine | [2-(...)
Affinity DataKi:  156nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307504(2-(Biphenyl-3-ylthio)-N,N-dimethylethanamine | CHE...)
Affinity DataKi:  516nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307493(2-(Biphenyl-2-ylthio)-N,N-dimethylethanamine | CHE...)
Affinity DataKi:  553nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307495(2-(2'-Methoxybiphenyl-2-yloxy)-N,N-dimethyl-ethana...)
Affinity DataKi:  669nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307505(2-(3-Bromophenylthio)-N,N-dimethylethanamine | CHE...)
Affinity DataKi:  676nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307487(2-(6-Bromopyridin-2-yloxy)-N,N-dimethylethan-amine...)
Affinity DataKi:  902nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307488(2-(6-(2,6-Dimethylphenyl)pyridin-2-ylthio)-N,Ndime...)
Affinity DataKi:  927nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307496(2-(2',6'-dimethylbiphenyl-2-ylthio)-N,N-dimethylet...)
Affinity DataKi:  1.43E+3nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307500(2-(4-(2,6-Dimethoxyphenyl)pyrimidin-2-yl)-N,Ndimet...)
Affinity DataKi:  1.49E+3nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307489(2-(6-(2,6-Dimethylphenyl)pyridin-2-yloxy)-N,Ndimet...)
Affinity DataKi:  1.61E+3nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307487(2-(6-Bromopyridin-2-yloxy)-N,N-dimethylethan-amine...)
Affinity DataKi:  2.24E+3nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307503(2-(2,6-Dimethylbiphenyl-3-ylthio)-N,N-dimethyl eth...)
Affinity DataKi:  2.35E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307492(2-(2-Bromophenoxy)-N,N-dimethylethanamine | CHEMBL...)
Affinity DataKi:  2.66E+3nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307491(2-(2-Bromophenylthio)-N,N-dimethylethanamine | CHE...)
Affinity DataKi:  4.11E+3nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307489(2-(6-(2,6-Dimethylphenyl)pyridin-2-yloxy)-N,Ndimet...)
Affinity DataKi:  7.22E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307499(2-(5-(2,6-Dimethoxyphenyl)-1,2,4-triazin-3-yl)-N,N...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307498(2-(5-(2,6-Dimethylphenyl)-1,2,4-triazin-3-yl)-N,Nd...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307497(N,N-Dimethyl-2-(5-phenyl-1,2,4-triazin-3-yl)-ethan...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50307502(7-(2,6-dimethylphenyl)-N,N-dimethylchroman-3-amine...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed