Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50031126
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307793(4-Acetamidophenyl 2-(4-(2-(trifluoromethyl)pyridin...)
Affinity DataIC50: 100nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307792(4-Acetamidophenyl 2-(4-(2-(trifluoromethyl)pyridin...)
Affinity DataIC50: 182nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307796(4-Acetamidophenyl 2-(2-(4-(2-(trifluoromethyl)pyri...)
Affinity DataIC50: 730nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307799(4-Acetamidophenyl 2-(4-(2-(trifluoromethyl)pyridin...)
Affinity DataIC50: 870nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307794(2-(4-isobutylphenyl)-N-(3-methylpyridin-2-yl)propa...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307795(4-Acetamidophenyl 3-(4-(2-(trifluoromethyl)pyridin...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307793(4-Acetamidophenyl 2-(4-(2-(trifluoromethyl)pyridin...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant MGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307792(4-Acetamidophenyl 2-(4-(2-(trifluoromethyl)pyridin...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant MGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307797(4-Acetamidophenyl 2-(2-(4-(2-(trifluoromethyl)pyri...)
Affinity DataIC50: 2.57E+3nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307802(4-Acetamidophenyl 4-(2-(trifluoromethyl)pyridin-4-...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307798(4-Acetamidophenyl 2-(3-methyl-4-(2-(trifluoromethy...)
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307809(4-Acetamidophenyl 5-chloro-2-(2-(trifluoromethyl)p...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307801(4-Acetamidophenyl 3-methyl-4-(2-(trifluoromethyl)p...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307806(4-Acetamidophenyl 2-(3-(trifluoromethyl)phenylamin...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307796(4-Acetamidophenyl 2-(2-(4-(2-(trifluoromethyl)pyri...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human recombinant MGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307800(4-Acetamidophenyl 4-((2-(trifluoromethyl)pyridin-4...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307807(4-Acetamidophenyl 4-chloro-2-(2-(trifluoromethyl)p...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307808(4-Acetamidophenyl 5-methyl-2-(2-(trifluoromethyl)p...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307803(4-Acetamidophenyl 3-(2-(trifluoromethyl)pyridin-4-...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307805(4-Acetamidophenyl 2-(2-(trifluoromethyl)pyridin-4-...)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307810(4-Acetamidophenyl 2-(2-(trifluoromethyl)pyridin-4-...)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 2.40E+5nMpH: 7.4Assay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate at pH 7.4 by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 2.63E+5nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307804(4-Acetamidophenyl 2-(3-(trifluoromethyl)phenylamin...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM26197(Paracetamol | acetaminophen | CHEMBL112 | N-(4-hyd...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 5.00E+5nMpH: 9.0Assay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate at pH 9.0 by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307793(4-Acetamidophenyl 2-(4-(2-(trifluoromethyl)pyridin...)
Affinity DataKi:  160nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by time-dependent studiesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50307792(4-Acetamidophenyl 2-(4-(2-(trifluoromethyl)pyridin...)
Affinity DataKi:  190nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by time-dependent studiesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed