Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50039063
TargetMelanocyte-stimulating hormone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308325((+/-)-Diphenyl{[6-(1H-indazol-3-ylmethyl)-5,7-diox...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC1R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308332((+/-)-2-{6-[(6-Fluoro-1H-indazol-3-yl)methyl]-4-me...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC4R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308331((+/-)-2-[6-(1H-Indazol-3-ylmethyl)-5,7-dioxo-4-(ph...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC4R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308330((+/-)-2-(6-((1H-indazol-3-yl)methyl)-6-methoxy-5,7...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC4R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308329((+/-)-2-[6-(1H-Indazol-3-ylmethyl)-5,7-dioxo-4-phe...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC4R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308328((+/-)-Phenyl hydrogen{[6-(1H-indazol-3-ylmethyl)-5...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC1R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308328((+/-)-Phenyl hydrogen{[6-(1H-indazol-3-ylmethyl)-5...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC4R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308327((+/-)-2-{6-[(1-Ethyl-1H-indazol-3-yl)methyl]-5,7-d...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC1R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308327((+/-)-2-{6-[(1-Ethyl-1H-indazol-3-yl)methyl]-5,7-d...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC4R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308326((+/-)-N-(1-methylethyl)-2-{6-[(1-methyl-1H-indazol...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC1R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308326((+/-)-N-(1-methylethyl)-2-{6-[(1-methyl-1H-indazol...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC4R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308319((S)-2-[2,4-Dioxo-3-(1H-indazol-3-ylmethylene)-5-ph...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human MC4R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308325((+/-)-Diphenyl{[6-(1H-indazol-3-ylmethyl)-5,7-diox...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC4R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308324((+/-)-2-[4-Cyclohexyl-6-(1H-indazol-3-ylmethyl)-5,...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC1R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308324((+/-)-2-[4-Cyclohexyl-6-(1H-indazol-3-ylmethyl)-5,...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC4R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308323((+/-)-2-[4-Cyclohexyl-5,7-dioxo-6-(phenylmethyl)-4...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC1R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308323((+/-)-2-[4-Cyclohexyl-5,7-dioxo-6-(phenylmethyl)-4...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC4R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50378664(CHEMBL1237150)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC4R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308321((S)-2-[2,4-Dioxo-3-(6-fluoro-1H-indazol-3-ylmethyl...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC1R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308321((S)-2-[2,4-Dioxo-3-(6-fluoro-1H-indazol-3-ylmethyl...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human MC4R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308320((S)-2-[2,4-Dioxo-3-(1H-indazol-3-ylmethylene)-5-ph...)
Affinity DataEC50:  3.16E+4nMAssay Description:Agonist activity at human MC1R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308320((S)-2-[2,4-Dioxo-3-(1H-indazol-3-ylmethylene)-5-ph...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human MC4R expressed in CHO cells after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed