Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50031501
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314332(4-hydroxy-2-((1-methyl-4-phenyl-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314317((Z)-1-(2-((4-(4-(3-oxa-8-azabicyclo[3.2.1]octane-8...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314327((Z)-1-(2-((4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314322((Z)-1-(2-((4-(2-oxa-5-azabicyclo[2.2.2]octan-5-yl)...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314339((Z)-1-(2-((4-(4-(3-methoxypyrrolidine-1-carbonyl)p...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314342((Z)-1-(2-((1-methyl-4-(4-(pyrrolidine-1-carbonyl)p...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314335((Z)-N-methyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin-3-...)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314338((Z)-1-(1-methyl-3-((3-oxo-5-(3-pyridin-3-ylureido)...)
Affinity DataIC50: 9nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314336((Z)-N-methyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin-3-...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314329((Z)-1-(2-((4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)...)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314320((Z)-N,N-dimethyl-1-(1-methyl-3-((3-oxo-5-(3-pyridi...)
Affinity DataIC50: 10.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314337((Z)-N-methyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin-3-...)
Affinity DataIC50: 10.9nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314340((Z)-1-(2-((4-(4-(3-(dimethylamino)pyrrolidine-1-ca...)
Affinity DataIC50: 11nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314333((Z)-N-methyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin-3-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314325((Z)-1-(2-((4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)...)
Affinity DataIC50: 14.3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314316((Z)-1-(2-((4-(4-(8-oxa-3-azabicyclo[3.2.1]octane-3...)
Affinity DataIC50: 17nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314318((Z)-1-(2-((1-methyl-4-(4-(morpholine-4-carbonyl)pi...)
Affinity DataIC50: 18nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314327((Z)-1-(2-((4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)...)
Affinity DataIC50: 24nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314324((Z)-1-(2-((4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)...)
Affinity DataIC50: 29nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314331((Z)-1-methyl-3-(2-((1-methyl-4-phenyl-1H-pyrrolo[2...)
Affinity DataIC50: 37nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314321((Z)-1-(2-((4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)...)
Affinity DataIC50: 42nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314341((Z)-1-(2-((1-methyl-4-(4-(piperidine-1-carbonyl)pi...)
Affinity DataIC50: 47.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314328((Z)-1-(2-((4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)...)
Affinity DataIC50: 57nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314343((Z)-1-(2-((1-methyl-4-(4-(4-methylpiperazine-1-car...)
Affinity DataIC50: 70nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314323((Z)-1-(2-((1-methyl-4-morpholino-1H-pyrrolo[2,3-b]...)
Affinity DataIC50: 71nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314332(4-hydroxy-2-((1-methyl-4-phenyl-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50: 89nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314334((Z)-N-benzyl-N-methyl-1-(1-methyl-3-((3-oxo-5-(3-p...)
Affinity DataIC50: 103nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314319((Z)-N,N-diethyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin...)
Affinity DataIC50: 115nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314321((Z)-1-(2-((4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)...)
Affinity DataIC50: 128nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314326((Z)-1-(2-((4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)...)
Affinity DataIC50: 145nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314331((Z)-1-methyl-3-(2-((1-methyl-4-phenyl-1H-pyrrolo[2...)
Affinity DataIC50: 233nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314322((Z)-1-(2-((4-(2-oxa-5-azabicyclo[2.2.2]octan-5-yl)...)
Affinity DataIC50: 249nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314323((Z)-1-(2-((1-methyl-4-morpholino-1H-pyrrolo[2,3-b]...)
Affinity DataIC50: 275nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314319((Z)-N,N-diethyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin...)
Affinity DataIC50: 308nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314328((Z)-1-(2-((4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)...)
Affinity DataIC50: 311nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314326((Z)-1-(2-((4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)...)
Affinity DataIC50: 498nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314329((Z)-1-(2-((4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)...)
Affinity DataIC50: 580nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314341((Z)-1-(2-((1-methyl-4-(4-(piperidine-1-carbonyl)pi...)
Affinity DataIC50: 600nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314342((Z)-1-(2-((1-methyl-4-(4-(pyrrolidine-1-carbonyl)p...)
Affinity DataIC50: 909nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314337((Z)-N-methyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin-3-...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314336((Z)-N-methyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin-3-...)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314335((Z)-N-methyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin-3-...)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314316((Z)-1-(2-((4-(4-(8-oxa-3-azabicyclo[3.2.1]octane-3...)
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314320((Z)-N,N-dimethyl-1-(1-methyl-3-((3-oxo-5-(3-pyridi...)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314325((Z)-1-(2-((4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)...)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314324((Z)-1-(2-((4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)...)
Affinity DataIC50: 2.22E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314339((Z)-1-(2-((4-(4-(3-methoxypyrrolidine-1-carbonyl)p...)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314318((Z)-1-(2-((1-methyl-4-(4-(morpholine-4-carbonyl)pi...)
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314317((Z)-1-(2-((4-(4-(3-oxa-8-azabicyclo[3.2.1]octane-8...)
Affinity DataIC50: 3.48E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314330((Z)-1-methyl-3-(2-((1-methyl-4-phenyl-1H-pyrrolo[2...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
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