Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50031547
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315150(isopropyl 4-((6-(4-(thiophen-2-ylsulfonyl)piperazi...)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315164(isopropyl 4-(2-(6-(4-(propylsulfonyl)piperazin-1-y...)
Affinity DataEC50:  700nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315163(isopropyl 4-(2-(6-(4-(ethylsulfonyl)piperazin-1-yl...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315162(isopropyl 4-(6-(4-(ethylsulfonyl)piperazin-1-yl)py...)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315161(N-(4-isopropylphenyl)-4-((6-(4-(propylsulfonyl)pip...)
Affinity DataEC50:  900nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315160(morpholino(4-((6-(4-(propylsulfonyl)piperazin-1-yl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315159(furan-2-yl(4-((6-(4-(propylsulfonyl)piperazin-1-yl...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315158(2,2-difluoro-1-(4-((6-(4-(propylsulfonyl)piperazin...)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315157(N-cyclohexyl-4-((6-(4-(propylsulfonyl)piperazin-1-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315156(3,3-dimethyl-1-(4-((6-(4-(propylsulfonyl)piperazin...)
Affinity DataEC50:  2.80E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315155(N-tert-butyl-4-((6-(4-(propylsulfonyl)piperazin-1-...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315154(3-methyl-1-(4-((6-(4-(propylsulfonyl)piperazin-1-y...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315153(N-isopropyl-4-((6-(4-(propylsulfonyl)piperazin-1-y...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315152(isopropyl 4-((6-(4-(piperidin-1-ylsulfonyl)piperaz...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315151(isopropyl 4-((6-(4-(N,N-diethylsulfamoyl)piperazin...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315136(N-(4-(1H-1,2,4-triazol-1-yl)phenyl)-5-nitro-6-(4-(...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human GPR119 receptor by cAMP mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315149(isopropyl 4-((6-(4-(pyridin-3-ylsulfonyl)piperazin...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315148(isopropyl 4-((6-(4-(cyclohexylmethylsulfonyl)piper...)
Affinity DataEC50:  90nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315147(isopropyl 4-((6-(4-(cyclohexylsulfonyl)piperazin-1...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315146(isopropyl 4-((6-(4-(2-methoxyethylsulfonyl)piperaz...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315145(isopropyl 4-((6-(4-(butylsulfonyl)piperazin-1-yl)p...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315144(isopropyl 4-((6-(4-(propylsulfonyl)piperazin-1-yl)...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315143(isopropyl 4-((6-(4-(isopropylsulfonyl)piperazin-1-...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315142(isopropyl 4-((6-(4-(ethylsulfonyl)piperazin-1-yl)p...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315141(isopropyl 4-((6-(4-(2-methoxyethyl)piperazin-1-yl)...)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315140(isopropyl 4-((6-(4-(furan-2-carbonyl)piperazin-1-y...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315139(isopropyl 4-((6-(4-acetylpiperazin-1-yl)pyridin-3-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315138(isopropyl 4-((6-(4-(2-hydroxy-2-(isopropylamino)et...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315137(isopropyl 4-((6-(4-(dimethylcarbamoyl)piperazin-1-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed