Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50031553
TargetLysosomal acid glucosylceramidase(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50315255((2R,3S,4S,5R)-2-hexylpiperidine-3,4,5-triol | CHEM...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant beta-glucocerebrosidase assessed as p-nitrophenolate accumulation preincubated for 10 mins before p-nitrophenyl-beta-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50315252((2R,3S,4S,5R)-2-propylpiperidine-3,4,5-triol | CHE...)
Affinity DataIC50: 560nMAssay Description:Inhibition of human recombinant beta-glucocerebrosidase assessed as p-nitrophenolate accumulation preincubated for 10 mins before p-nitrophenyl-beta-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM18362((2R,3S,4R,5R,6R)-2-hexyl-6-(hydroxymethyl)piperidi...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant beta-glucocerebrosidase preincubated for 10 mins before 4-methylumbelliferyl-betaD-glucopyranoside addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50315254((2R,3S,4R,5R,6S)-2-hexyl-6-(hydroxymethyl)piperidi...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of human recombinant beta-glucocerebrosidase assessed as p-nitrophenolate accumulation preincubated for 10 mins before p-nitrophenyl-beta-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM18361((2R,3S,4R,5R,6R)-2-butyl-6-(hydroxymethyl)piperidi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant beta-glucocerebrosidase preincubated for 10 mins before 4-methylumbelliferyl-betaD-glucopyranoside addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50315253((2S,3S,4R,5R,6S)-2-butyl-6-(hydroxymethyl)piperidi...)
Affinity DataIC50: 1.47E+5nMAssay Description:Inhibition of human recombinant beta-glucocerebrosidase assessed as p-nitrophenolate accumulation preincubated for 10 mins before p-nitrophenyl-beta-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM18360((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-propylpiperid...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of human recombinant beta-glucocerebrosidase preincubated for 10 mins before 4-methylumbelliferyl-betaD-glucopyranoside addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50315251((2S,3R,4R,5S,6S)-2-(hydroxymethyl)-6-propylpiperid...)
Affinity DataIC50: 4.87E+5nMAssay Description:Inhibition of human recombinant beta-glucocerebrosidase assessed as p-nitrophenolate accumulation preincubated for 10 mins before p-nitrophenyl-beta-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50315250((2R,3S,4S,5R)-2-nonylpiperidine-3,4,5-triol | CHEM...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of human recombinant beta-glucocerebrosidase assessed as p-nitrophenolate accumulation preincubated for 10 mins before p-nitrophenyl-beta-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed