Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50031554
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315265(Methyl{5-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-p...)
Affinity DataEC50:  8.10nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315262(Methyl{4-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-p...)
Affinity DataEC50:  10.3nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315267(Methyl{5-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-p...)
Affinity DataEC50:  25.7nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315256(Methyl{3-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-p...)
Affinity DataEC50:  50.1nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315259(Methyl 3-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-p...)
Affinity DataEC50:  51.5nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315257(9-benzyl-2-butoxy-8-oxoadenine | 6-Amino-9-benzyl-...)
Affinity DataEC50:  63.7nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315260(Methyl 4-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-p...)
Affinity DataEC50:  72.9nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315263(Methyl l 2-{3-[(6-amino-2-butoxy-8-oxo-7,8-dihydro...)
Affinity DataEC50:  75nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315264(Methyl 3-{3-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9...)
Affinity DataEC50:  87.5nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315266(Methyl{3-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-p...)
Affinity DataEC50:  108nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315268(Ethyl{3-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-pu...)
Affinity DataEC50:  188nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50241029(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
Affinity DataEC50:  260nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315269(Methyl{3-[(6-amino-2-methoxyethoxy-8-oxo-7,8-dihyd...)
Affinity DataEC50:  312nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50189516(9-benzyl-2-(2-methoxyethoxy)-8-oxoadenine | SM-360...)
Affinity DataEC50:  399nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315261(Methyl{2-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-p...)
Affinity DataEC50:  467nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315258(Methyl 2-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-p...)
Affinity DataEC50:  609nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50315256(Methyl{3-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-p...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at TLR8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed