Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50031565
TargetSqualene synthase(Rat)
University of Turin

Curated by ChEMBL
LigandPNGBDBM12577({1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonoprop...)
Affinity DataIC50: 640nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50315414((5-(4-Phenylsulfonylfurazan-3-yloxy)-1-hydroxypent...)
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50315415((5-(3-Phenylsulfonylfuroxan-4-yloxy)-1-hydroxypent...)
Affinity DataIC50: 7.95E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50315412(5-(4-Phenylfurazan-3-yloxy)pentylidenebis(phosphon...)
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50315413(5-(3-Phenylfuroxan-4-yloxy)pentylidenebis(phosphon...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed