Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50035955
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006687((S)-2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012036(2-({5-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012044(CHEMBL43454 | 2-({5-[Ethyl-(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012038(CHEMBL41609 | 2-({5-[(2-Fluoro-ethyl)-(2-methyl-4-...)
Affinity DataIC50: 160nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012022(CHEMBL290469 | 2-({5-[(2-Fluoro-ethyl)-(2-methyl-4...)
Affinity DataIC50: 190nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012051(CHEMBL44242 | 2-({5-[Ethyl-(2-fluoromethyl-4-oxo-3...)
Affinity DataIC50: 220nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012048(CHEMBL42626 | 2-({5-[Ethyl-(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50: 230nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012043(CHEMBL43080 | 2-({5-[(2-Methyl-4-oxo-3,4-dihydro-q...)
Affinity DataIC50: 230nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006691(CHEMBL40321 | (S)-2-(4-(methyl((2-methyl-4-oxo-3,4...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012045(2-{4-[Ethyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin...)
Affinity DataIC50: 260nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012019((S)-2-(5-(methyl((2-methyl-4-oxo-3,4-dihydroquinaz...)
Affinity DataIC50: 350nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012026(CHEMBL41225 | 2-({5-[(2-Hydroxy-ethyl)-(2-methyl-4...)
Affinity DataIC50: 420nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012029(CHEMBL44564 | 2-({5-[Methyl-(2-methyl-4-oxo-3,4-di...)
Affinity DataIC50: 420nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012031(CHEMBL418433 | 2-({5-[(2-Methyl-4-oxo-3,4-dihydro-...)
Affinity DataIC50: 440nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012052(CHEMBL40539 | 2-({5-[(2-Hydroxymethyl-4-oxo-3,4-di...)
Affinity DataIC50: 490nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012041(CHEMBL42315 | 2-({5-[(2-Fluoro-ethyl)-(2-methyl-4-...)
Affinity DataIC50: 550nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012025(CHEMBL40851 | 2-({5-[Ethyl-(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50: 580nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012040(CHEMBL290718 | 2-({5-[Methyl-(2-methyl-4-oxo-3,4-d...)
Affinity DataIC50: 670nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012037((S)-2-(5-(allyl((2-methyl-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50: 760nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012027(CHEMBL410300 | 2-({2-[Ethyl-(2-methyl-4-oxo-3,4-di...)
Affinity DataIC50: 760nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012049(CHEMBL42357 | 2-({5-[Ethyl-(2-fluoromethyl-4-oxo-3...)
Affinity DataIC50: 930nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012028(CHEMBL434973 | 2-({5-[Ethyl-(2-methyl-4-oxo-3,4-di...)
Affinity DataIC50: 940nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012039(CHEMBL435171 | 2-({5-[Ethyl-(2-hydroxymethyl-4-oxo...)
Affinity DataIC50: 1.03E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012042(CHEMBL41927 | 2-({5-[Allyl-(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50: 1.07E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012050(CHEMBL539936 | 2-({5-[(2-Fluoro-ethyl)-(2-fluorome...)
Affinity DataIC50: 1.07E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012032(CHEMBL40663 | 2-({5-[(2-Hydroxy-ethyl)-(2-methyl-4...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012034(CHEMBL289697 | 2-({5-[(2-Fluoromethyl-4-oxo-3,4-di...)
Affinity DataIC50: 1.36E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012053(CHEMBL41424 | 2-({5-[(2-Hydroxymethyl-4-oxo-3,4-di...)
Affinity DataIC50: 1.36E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012030(CHEMBL40877 | 2-({5-[Allyl-(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50: 1.68E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012035(CHEMBL40591 | 2-({5-[(3-Hydroxy-propyl)-(2-methyl-...)
Affinity DataIC50: 1.74E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012047(CHEMBL288307 | 2-({5-[(2-Methyl-4-oxo-3,4-dihydro-...)
Affinity DataIC50: 1.85E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012024(2-({5-[Methyl-(2-methyl-4-oxo-3,4-dihydro-quinazol...)
Affinity DataIC50: 2.34E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012020(CHEMBL44127 | 2-({5-[Cyanomethyl-(2-methyl-4-oxo-3...)
Affinity DataIC50: 3.08E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012033(CHEMBL40707 | 2-({5-[(3-Hydroxy-propyl)-(2-methyl-...)
Affinity DataIC50: 3.36E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50368273(CHEMBL1788164)
Affinity DataIC50: 4.25E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012046(CHEMBL42865 | 2-({5-[(2-Methyl-4-oxo-3,4-dihydro-q...)
Affinity DataIC50: 7.12E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012023(CHEMBL40739 | 2-({5-[(2-Methyl-4-oxo-3,4-dihydro-q...)
Affinity DataIC50: 2.48E+4nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed