Compile Data Set for Download or QSAR
Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 50031664
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316893(2-amino-4-phenyl-8-(2-(pyridin-2-yl)ethylamino)-5H...)
Affinity DataKi:  0.900nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316892(2-amino-4-phenyl-8-(2-(pyridin-4-yl)ethylamino)-5H...)
Affinity DataKi:  0.900nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316899(2-amino-8-(4-methylpiperazin-1-yl)-4-phenyl-5H-ind...)
Affinity DataKi:  2.70nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316898(2-amino-8-morpholino-4-phenyl-5H-indeno[1,2-d]pyri...)
Affinity DataKi:  2.90nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316895(2-Amino-8-[2-(1,1-dioxo-1lambda*6*-thiomorpholin-4...)
Affinity DataKi:  3.10nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316894(2-amino-8-(2-morpholinoethylamino)-4-phenyl-5H-ind...)
Affinity DataKi:  4.40nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316891(2-amino-8-((2-(dimethylamino)ethyl)(methyl)amino)-...)
Affinity DataKi:  4.70nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316897(2-amino-8-((1-ethylpiperidin-4-yl)(methyl)amino)-4...)
Affinity DataKi:  4.90nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316887(2-amino-8-(2-morpholinoethoxy)-4-phenyl-5H-indeno[...)
Affinity DataKi:  6.5nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316870(2-amino-N-(2-(diethylamino)ethyl)-N-methyl-5-oxo-4...)
Affinity DataKi:  7.80nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316883(2-amino-8-(2-(diethylamino)ethoxy)-4-phenyl-5H-ind...)
Affinity DataKi:  7.90nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316876(2-amino-8-(4-methylpiperazine-1-carbonyl)-4-phenyl...)
Affinity DataKi:  8.20nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316868(2-amino-8-(4-methyl-1,4-diazepan-1-yl)-4-phenyl-5H...)
Affinity DataKi:  10nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316877(2-amino-4-(4-fluorophenyl)-8-(4-methylpiperazine-1...)
Affinity DataKi:  11.1nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316900(2-amino-8-(4-ethylpiperazin-1-yl)-4-phenyl-5H-inde...)
Affinity DataKi:  11.4nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316875(2-amino-4-phenyl-8-(piperazine-1-carbonyl)-5H-inde...)
Affinity DataKi:  12.3nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316869(2-amino-N-(2-(dimethylamino)ethyl)-N-methyl-5-oxo-...)
Affinity DataKi:  12.4nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316896(2-amino-8-(1-ethylpiperidin-4-ylamino)-4-phenyl-5H...)
Affinity DataKi:  12.5nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316892(2-amino-4-phenyl-8-(2-(pyridin-4-yl)ethylamino)-5H...)
Affinity DataKi:  12.7nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316871(2-amino-N-(2-(diethylamino)ethyl)-5-oxo-4-phenyl-5...)
Affinity DataKi:  13.5nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316885(2-amino-8-(2-(diisopropylamino)ethoxy)-4-phenyl-5H...)
Affinity DataKi:  13.7nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316878(2-amino-8-(4-ethylpiperazine-1-carbonyl)-4-phenyl-...)
Affinity DataKi:  14.9nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316893(2-amino-4-phenyl-8-(2-(pyridin-2-yl)ethylamino)-5H...)
Affinity DataKi:  15.4nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316897(2-amino-8-((1-ethylpiperidin-4-yl)(methyl)amino)-4...)
Affinity DataKi:  16.4nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316874(2-amino-N-(1-isopropylpiperidin-4-yl)-5-oxo-4-phen...)
Affinity DataKi:  16.8nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316881(2-amino-8-(2-(dimethylamino)ethoxy)-4-phenyl-5H-in...)
Affinity DataKi:  17.3nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316888(2-amino-4-(4-fluorophenyl)-8-(2-morpholinoethoxy)-...)
Affinity DataKi:  18.1nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316873(2-amino-N-methyl-N-(1-methylpiperidin-4-yl)-5-oxo-...)
Affinity DataKi:  18.6nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316889(2-amino-4-phenyl-8-(2-(pyrrolidin-1-yl)ethoxy)-5H-...)
Affinity DataKi:  19.3nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316880(2-amino-8-(4-isopropylpiperazine-1-carbonyl)-4-phe...)
Affinity DataKi:  20.7nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316901(2-amino-8-(4-(cyclopropylmethyl)piperazin-1-yl)-4-...)
Affinity DataKi:  23.2nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316872(2-amino-N-(2-morpholinoethyl)-5-oxo-4-phenyl-5H-in...)
Affinity DataKi:  28.4nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316879(2-amino-8-(4-ethylpiperazine-1-carbonyl)-4-(4-fluo...)
Affinity DataKi:  32.1nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316898(2-amino-8-morpholino-4-phenyl-5H-indeno[1,2-d]pyri...)
Affinity DataKi:  32.4nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316875(2-amino-4-phenyl-8-(piperazine-1-carbonyl)-5H-inde...)
Affinity DataKi:  32.5nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316894(2-amino-8-(2-morpholinoethylamino)-4-phenyl-5H-ind...)
Affinity DataKi:  32.7nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316881(2-amino-8-(2-(dimethylamino)ethoxy)-4-phenyl-5H-in...)
Affinity DataKi:  33.3nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316890(8-(2-(7-azabicyclo[2.2.1]heptan-7-yl)ethoxy)-2-ami...)
Affinity DataKi:  35.1nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316886(2-amino-4-phenyl-8-(2-(piperidin-1-yl)ethoxy)-5H-i...)
Affinity DataKi:  35.3nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316899(2-amino-8-(4-methylpiperazin-1-yl)-4-phenyl-5H-ind...)
Affinity DataKi:  35.6nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316882(2-amino-8-(2-(dimethylamino)ethoxy)-4-(4-fluorophe...)
Affinity DataKi:  37.3nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316882(2-amino-8-(2-(dimethylamino)ethoxy)-4-(4-fluorophe...)
Affinity DataKi:  37.4nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316871(2-amino-N-(2-(diethylamino)ethyl)-5-oxo-4-phenyl-5...)
Affinity DataKi:  45.2nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316895(2-Amino-8-[2-(1,1-dioxo-1lambda*6*-thiomorpholin-4...)
Affinity DataKi:  46.7nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316887(2-amino-8-(2-morpholinoethoxy)-4-phenyl-5H-indeno[...)
Affinity DataKi:  48.2nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316884(2-amino-8-(2-(diethylamino)ethoxy)-4-(4-fluorophen...)
Affinity DataKi:  50.6nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316891(2-amino-8-((2-(dimethylamino)ethyl)(methyl)amino)-...)
Affinity DataKi:  57.3nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316876(2-amino-8-(4-methylpiperazine-1-carbonyl)-4-phenyl...)
Affinity DataKi:  58.4nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316878(2-amino-8-(4-ethylpiperazine-1-carbonyl)-4-phenyl-...)
Affinity DataKi:  67.4nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316902(2-amino-8-(2-(diisopropylamino)ethoxy)-4-(4-fluoro...)
Affinity DataKi:  76.6nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
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