Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50031599
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315998(N-((S)-1-((1S,2R,4R)-4-(ethyl(isopropyl)amino)-2-(...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315992(N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-...)
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315993(N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-...)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 45 mins in presence of 0.1 M bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315994(N-(2-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-(phe...)
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315989(3-fluoro-N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)...)
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315993(N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-...)
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315994(N-(2-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-(phe...)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 45 mins in presence of 0.1 M bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315998(N-((S)-1-((1S,2R,4R)-4-(ethyl(isopropyl)amino)-2-(...)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 45 mins in presence of 0.5 M bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315990(N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-...)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50316002((+/-)-tert-butyl 2-(2-((1S,2R)-2-(4-(methylthio)be...)
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human PBMC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315997(N-((S)-1-((1S,2R,4R)-4-(isopropyl(propyl)amino)-2-...)
Affinity DataIC50: 51nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315986(N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-...)
Affinity DataIC50: 99nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315991(N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-...)
Affinity DataIC50: 151nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315999(tert-butyl 2-((S)-1-((1S,2R)-2-(4-(methylthio)benz...)
Affinity DataIC50: 278nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human PBMC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315988(N-((S)-1-((1S,2R,4R)-4-(dimethylamino)-2-(phenylsu...)
Affinity DataIC50: 284nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50316000((+/-)-tert-butyl 2-((R)-1-((1S,2R)-2-(4-(methylthi...)
Affinity DataIC50: 312nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human PBMC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50316001(tert-butyl 2-(2-((1S,2R)-2-(4-(methylthio)benzylam...)
Affinity DataIC50: 460nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human PBMC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315996(N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315987(N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315992(N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315990(N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315995(N-(1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-((4-...)
Affinity DataIC50: 4.50E+3nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315995(N-(1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-((4-...)
Affinity DataIC50: 4.50E+3nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315989(3-fluoro-N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315993(N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315991(N-((S)-1-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315994(N-(2-((1S,2R,4R)-4-(isopropyl(methyl)amino)-2-(phe...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed