Compile Data Set for Download or QSAR
Report error Found 151 Enz. Inhib. hit(s) with all data for entry = 50039157
LigandPNGBDBM50318502(2-(1-(cyclopentylmethyl)-7-fluoro-2-oxoindolin-3-y...)
Affinity DataEC50:  510nMAssay Description:Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as increase in membrane currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318503(2-(1-(cyclopentylmethyl)-7-fluoro-2-oxoindolin-3-y...)
Affinity DataEC50:  660nMAssay Description:Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as increase in membrane currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318504(2-(7-chloro-1-isobutyl-2-oxoindolin-3-ylidene)acet...)
Affinity DataEC50:  610nMAssay Description:Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as increase in membrane currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318505(2-(1-(cyclobutylmethyl)-7-fluoro-2-oxoindolin-3-yl...)
Affinity DataEC50:  1.16E+3nMAssay Description:Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as increase in membrane currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318506(2-(1-(cyclopentylmethyl)-7-fluoro-2-oxoindolin-3-y...)
Affinity DataEC50:  3.76E+3nMAssay Description:Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as increase in membrane currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318507(1-(2-ethylbutyl)-7-fluoro-3-(2-morpholino-2-oxoeth...)
Affinity DataEC50:  1.29E+3nMAssay Description:Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as increase in membrane currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318508(2-(1-benzyl-5-fluoro-2-oxoindolin-3-ylidene)acetic...)
Affinity DataEC50:  4.45E+3nMAssay Description:Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as increase in membrane currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318509(2-(5-fluoro-1-isobutyl-2-oxoindolin-3-ylidene)acet...)
Affinity DataEC50:  4.63E+3nMAssay Description:Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as increase in membrane currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318510(1-benzyl-3-(thiazol-2-ylmethylene)indolin-2-one | ...)
Affinity DataEC50:  5.65E+3nMAssay Description:Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as increase in membrane currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318511(dibenzo[b,f][1,4]oxazepine | CHEMBL1085100)
Affinity DataEC50:  0.302nMAssay Description:Activation of human TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318512(benzyl bromide | CHEMBL1085946)
Affinity DataEC50:  1.20E+4nMAssay Description:Activation of human TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318513(bromo acetone | CHEMBL1085947)
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of human TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318514(ethyl bromo acetate | CHEMBL1085948)
Affinity DataEC50:  39nMAssay Description:Activation of human TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318515(bromo benzyl cyanide | CHEMBL1085832)
Affinity DataEC50:  10nMAssay Description:Activation of human TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318455(AMG-9090 | N-(2,2,2-trichloro-1-(4-chlorophenylthi...)
Affinity DataEC50:  66nMAssay Description:Agonist activity at TRPA1 channel in rat DRG neurons assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318456(AMG-5445 | 4-methoxy-N-(2,2,2-trichloro-1-(4-chlor...)
Affinity DataEC50:  115nMAssay Description:Agonist activity at TRPA1 channel in rat DRG neurons assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318462(4-methyl-N-(2,2,2-trichloro-1-(4-nitrophenylthio)e...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at TRPA1 channel in rat DRG neurons assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318461(4-methyl-N-(2,2,2-trichloro-1-(4-chlorophenylthio)...)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at TRPA1 channel in rat DRG neurons assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318460(S-2,2,2-trichloro-1-(4-chlorobenzamido)ethyl ethan...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at TRPA1 channel in rat DRG neurons assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318463(2-(1,3-dimethyl-2,6-dioxo-2,3-dihydro-1H-purin-7(6...)
Affinity DataEC50:  1.00E+6nMAssay Description:Activation of mouse TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318464(N-(4-sec-butylphenyl)-2-(1,3-dimethyl-2,6-dioxo-2,...)
Affinity DataEC50:  2.50E+6nMAssay Description:Activation of mouse TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50203072(Allylisothiocyanate | 3-isothiocyanatoprop-1-ene |...)
Affinity DataEC50:  1.90E+3nMAssay Description:Activation of TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50203068(Propargyl isothiocyanate | 3-isothiocyanatoprop-1-...)
Affinity DataEC50:  1.84E+4nMAssay Description:Activation of TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50240520(benzyl isothiocyanate | BITC, 17 | Isothiocyanic a...)
Affinity DataEC50:  319nMAssay Description:Activation of TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50240850(phenethylisothiocyanate | Phenethyl isothiocyanate...)
Affinity DataEC50:  1.00E+4nMAssay Description:Activation of TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50203071((2-aminoethyl)methanethiosulphonate | S-2-aminoeth...)
Affinity DataEC50:  1.58E+6nMAssay Description:Activation of TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50034278(2-((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienyls...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at human TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50174225(((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylsul...)
Affinity DataEC50:  9.00E+4nMAssay Description:Agonist activity at human TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at human TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318476(CHEMBL356479 | Chlordantoin | 5-(1-Ethyl-pentyl)-3...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at human TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50203065(3-phenylprop-2-enal | cinnamaldehyde | 3-phenylacr...)
Affinity DataEC50:  6.50E+3nMAssay Description:Activation of TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318477(Hydroxy-alpha-sanshool | CHEMBL1084610)
Affinity DataEC50:  6.60E+3nMAssay Description:Activation of TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318477(Hydroxy-alpha-sanshool | CHEMBL1084610)
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of TRPV1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50276351(4-(prop-1-en-2-yl)cyclohex-1-ene-1-carbaldehyde | ...)
Affinity DataEC50:  4.10E+4nMAssay Description:Activation of TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50276352(perillaketone | CHEMBL469753)
Affinity DataEC50:  1.97E+4nMAssay Description:Activation of TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318478(miogadial | CHEMBL1084611)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318479((1R,4aS,8aS)-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-oc...)
Affinity DataEC50:  59nMAssay Description:Agonist activity at human TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318480(Miogatrial | CHEMBL1085849)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM61009(cid_37839 | Isovelleral | marasmane | (1aS,3aS,6aS...)
Affinity DataEC50:  1.30E+5nMAssay Description:Agonist activity at TRPA1 channel in mouse dorsal root ganglion cells assessed as increase in intracellular calcium influx by radiometric Ca2+ imagin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM61009(cid_37839 | Isovelleral | marasmane | (1aS,3aS,6aS...)
Affinity DataEC50:  590nMAssay Description:Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM61009(cid_37839 | Isovelleral | marasmane | (1aS,3aS,6aS...)
Affinity DataEC50:  2.58E+3nMAssay Description:Agonist activity at mouse TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50240432(5-methyl-2-(propan-2-yl)phenol | thymol | 1-hydrox...)
Affinity DataEC50:  6.00E+3nMAssay Description:Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50240432(5-methyl-2-(propan-2-yl)phenol | thymol | 1-hydrox...)
Affinity DataEC50:  6.25E+4nMAssay Description:Activation of TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50240433(CHEMBL281202 | 5-Isopropyl-2-methyl-phenol | CARVA...)
Affinity DataEC50:  7.00E+3nMAssay Description:Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataEC50:  1.70E+4nMAssay Description:Activation of TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataEC50:  230nMAssay Description:Agonist activity at rat TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318483(Tetrahydrocannabinol acid | CHEMBL1086558)
Affinity DataEC50:  240nMAssay Description:Agonist activity at rat TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318484(CHEMBL190461 | 2-((1R,6R)-6-Isopropenyl-3-methyl-c...)
Affinity DataEC50:  96nMAssay Description:Agonist activity at rat TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318485(Cannabidiol acid | 2,4-dihydroxy-3-((1R,6R)-3-meth...)
Affinity DataEC50:  1.20E+4nMAssay Description:Agonist activity at rat TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318486(CHEMBL422704 | 2-Methyl-2-(4-methyl-pent-3-enyl)-7...)
Affinity DataEC50:  60nMAssay Description:Agonist activity at rat TRPA1 channel expressed in HEK293 cells assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 151 total ) | Next | Last >>
Jump to: