Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50031637
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316543(N,N'-(Propane-1,3-diyl)bis(6,7-dihydroxy-2-imino-2...)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316542(N,N'-(Propane-1,3-diyl)bis(7,8-dihydroxy-2-imino-2...)
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316539(N,N'-(Ethane-1,2-diyl)bis(7,8-dihydroxy-2-imino-2H...)
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316542(N,N'-(Propane-1,3-diyl)bis(7,8-dihydroxy-2-imino-2...)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316541(N,N'-(Propane-1,3-diyl)bis(7-hydroxy-2-imino-2H-ch...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316540(N,N'-(Propane-1,3-diyl)bis(8-hydroxy-2-imino-2H-ch...)
Affinity DataIC50: 3.48E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDynamin-1(Rat)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316543(N,N'-(Propane-1,3-diyl)bis(6,7-dihydroxy-2-imino-2...)
Affinity DataIC50: 4.04E+4nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316540(N,N'-(Propane-1,3-diyl)bis(8-hydroxy-2-imino-2H-ch...)
Affinity DataIC50: 4.82E+4nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDynamin-1(Rat)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316541(N,N'-(Propane-1,3-diyl)bis(7-hydroxy-2-imino-2H-ch...)
Affinity DataIC50: 6.61E+4nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316543(N,N'-(Propane-1,3-diyl)bis(6,7-dihydroxy-2-imino-2...)
Affinity DataIC50: 7.46E+4nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDynamin-1(Rat)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316542(N,N'-(Propane-1,3-diyl)bis(7,8-dihydroxy-2-imino-2...)
Affinity DataIC50: 9.95E+4nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316539(N,N'-(Ethane-1,2-diyl)bis(7,8-dihydroxy-2-imino-2H...)
Affinity DataIC50: 1.30E+6nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed