Compile Data Set for Download or QSAR
Report error Found 127 Enz. Inhib. hit(s) with all data for entry = 50031804
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319623(4-(2,4-Dimethylthiazol-5-yl)-N-(3,4,5-trimethoxyph...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319622(N,4-Dimethyl-5-(2-(3,4,5-trimethoxyphenylamino)pyr...)
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319623(4-(2,4-Dimethylthiazol-5-yl)-N-(3,4,5-trimethoxyph...)
Affinity DataKi:  2nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50229973(4-methyl-5-(2-(3-nitrophenylamino)pyrimidin-4-yl)t...)
Affinity DataKi:  2nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319622(N,4-Dimethyl-5-(2-(3,4,5-trimethoxyphenylamino)pyr...)
Affinity DataKi:  3nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319621(N-Ethyl-4-methyl-5-(2-(3,4,5-trimethoxyphenylamino...)
Affinity DataKi:  3nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319616(1-(4-(4-(4-(2-Amino-4-methylthiazol-5-yl)pyrimidin...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319620(N-(4-(4-(2-(Ethylamino)-4-methylthiazol-5-yl)pyrim...)
Affinity DataKi:  4nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319619(Aminopyrimidine, 5 | CHEMBL1085626 | 4-(2,4-Dimeth...)
Affinity DataKi:  4nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50229973(4-methyl-5-(2-(3-nitrophenylamino)pyrimidin-4-yl)t...)
Affinity DataKi:  4nMAssay Description:Inhibition of CDK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319620(N-(4-(4-(2-(Ethylamino)-4-methylthiazol-5-yl)pyrim...)
Affinity DataKi:  5nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319617(N-Ethyl-4-methyl-5-(2-(4-morpholinophenylamino)pyr...)
Affinity DataKi:  6nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319621(N-Ethyl-4-methyl-5-(2-(3,4,5-trimethoxyphenylamino...)
Affinity DataKi:  6nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319622(N,4-Dimethyl-5-(2-(3,4,5-trimethoxyphenylamino)pyr...)
Affinity DataKi:  6nMAssay Description:Inhibition of CDK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM8066(4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1...)
Affinity DataKi:  6.90nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319616(1-(4-(4-(4-(2-Amino-4-methylthiazol-5-yl)pyrimidin...)
Affinity DataKi:  7.60nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50277583(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...)
Affinity DataKi:  8nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319627(1-(4-(4-(4-(2,4-Dimethylthiazol-5-yl)pyrimidin-2-y...)
Affinity DataKi:  8.20nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319619(Aminopyrimidine, 5 | CHEMBL1085626 | 4-(2,4-Dimeth...)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319620(N-(4-(4-(2-(Ethylamino)-4-methylthiazol-5-yl)pyrim...)
Affinity DataKi:  9nMAssay Description:Inhibition of CDK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50277583(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...)
Affinity DataKi:  9.20nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319626(4-(2,4-Dimethylthiazol-5-yl)-N-(4-(4-(methylsulfon...)
Affinity DataKi:  9.20nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319618(N,4-Dimethyl-5-(2-(4-morpholinophenylamino)pyrimid...)
Affinity DataKi:  9.40nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319615(1-(4-(4-(4-(4-Methyl-2-(methylamino)thiazol-5-yl)p...)
Affinity DataKi:  9.70nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319623(4-(2,4-Dimethylthiazol-5-yl)-N-(3,4,5-trimethoxyph...)
Affinity DataKi:  11nMAssay Description:Inhibition of CDK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319615(1-(4-(4-(4-(4-Methyl-2-(methylamino)thiazol-5-yl)p...)
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319627(1-(4-(4-(4-(2,4-Dimethylthiazol-5-yl)pyrimidin-2-y...)
Affinity DataKi:  13nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319617(N-Ethyl-4-methyl-5-(2-(4-morpholinophenylamino)pyr...)
Affinity DataKi:  14nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM8066(4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1...)
Affinity DataKi:  15nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319626(4-(2,4-Dimethylthiazol-5-yl)-N-(4-(4-(methylsulfon...)
Affinity DataKi:  18nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319625(N1-(4-(2,4-Dimethylthiazol-5-yl)pyrimidin-2-yl)-N4...)
Affinity DataKi:  18nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319618(N,4-Dimethyl-5-(2-(4-morpholinophenylamino)pyrimid...)
Affinity DataKi:  19nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319615(1-(4-(4-(4-(4-Methyl-2-(methylamino)thiazol-5-yl)p...)
Affinity DataKi:  22nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319624(Aminopyrimidine, 4 | CHEMBL1084454 | N1-(4-(2,4-Di...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319620(N-(4-(4-(2-(Ethylamino)-4-methylthiazol-5-yl)pyrim...)
Affinity DataKi:  32nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319625(N1-(4-(2,4-Dimethylthiazol-5-yl)pyrimidin-2-yl)-N4...)
Affinity DataKi:  33nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319620(N-(4-(4-(2-(Ethylamino)-4-methylthiazol-5-yl)pyrim...)
Affinity DataKi:  38nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50277583(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...)
Affinity DataKi:  44nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50277583(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...)
Affinity DataKi:  44nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50229973(4-methyl-5-(2-(3-nitrophenylamino)pyrimidin-4-yl)t...)
Affinity DataKi:  53nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50229973(4-methyl-5-(2-(3-nitrophenylamino)pyrimidin-4-yl)t...)
Affinity DataKi:  57nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50229973(4-methyl-5-(2-(3-nitrophenylamino)pyrimidin-4-yl)t...)
Affinity DataKi:  70nMAssay Description:Inhibition of CDK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50229973(4-methyl-5-(2-(3-nitrophenylamino)pyrimidin-4-yl)t...)
Affinity DataKi:  73nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50229973(4-methyl-5-(2-(3-nitrophenylamino)pyrimidin-4-yl)t...)
Affinity DataKi:  80nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319617(N-Ethyl-4-methyl-5-(2-(4-morpholinophenylamino)pyr...)
Affinity DataKi:  151nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319618(N,4-Dimethyl-5-(2-(4-morpholinophenylamino)pyrimid...)
Affinity DataKi:  156nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319624(Aminopyrimidine, 4 | CHEMBL1084454 | N1-(4-(2,4-Di...)
Affinity DataKi:  168nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319620(N-(4-(4-(2-(Ethylamino)-4-methylthiazol-5-yl)pyrim...)
Affinity DataKi:  171nMAssay Description:Inhibition of CDK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319617(N-Ethyl-4-methyl-5-(2-(4-morpholinophenylamino)pyr...)
Affinity DataKi:  196nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Cyclacel

Curated by ChEMBL
LigandPNGBDBM50319623(4-(2,4-Dimethylthiazol-5-yl)-N-(3,4,5-trimethoxyph...)
Affinity DataKi:  239nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
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