Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50031808
LigandPNGBDBM50319684(1-(2,2'-bipyridin-5-yl)-3-(4-(piperidin-1-yl)butyl...)
Affinity DataEC50:  390nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319680(1-(6-phenylpyridin-3-yl)-3-(4-(piperidin-1-yl)buty...)
Affinity DataEC50:  120nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319679(1-(4-Piperidin-1-ylbutyl)-3-(4-pyridin-2-ylphenyl)...)
Affinity DataEC50:  130nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319678(1-(4-(6-fluoropyridin-3-yl)phenyl)-3-(4-(piperidin...)
Affinity DataEC50:  120nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319677(1-(4'-fluorobiphenyl-4-yl)-3-(4-(piperidin-1-yl)bu...)
Affinity DataEC50:  220nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319676(1-(2'-fluorobiphenyl-4-yl)-3-(4-(piperidin-1-yl)bu...)
Affinity DataEC50:  130nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319675(1-(2'-methoxybiphenyl-4-yl)-3-(4-(piperidin-1-yl)b...)
Affinity DataEC50:  140nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319674(1-(biphenyl-4-yl)-3-(4-(piperidin-1-yl)butyl)urea ...)
Affinity DataEC50:  260nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319681(1-(6-(2-methoxyphenyl)pyridin-3-yl)-3-(4-(piperidi...)
Affinity DataEC50:  230nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319683(1-(6'-fluoro-2,3'-bipyridin-5-yl)-3-(4-(piperidin-...)
Affinity DataEC50:  530nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319672(1-(4-(Morpholin-4-yl)butyl)-3-(4-pyridin-3-ylpheny...)
Affinity DataEC50:  490nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319671(1-(4-Piperidin-1-yl)butyl-3-(4-pyridin-3-ylphenyl)...)
Affinity DataEC50:  120nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319670(6-Piperidin-1-ylhexanoic acid(4-pyridin-3-yl-pheny...)
Affinity DataEC50:  890nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50300803(5-(piperidin-1-yl)-N-(4-(pyridin-3-yl)phenyl)penta...)
Affinity DataEC50:  350nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50300802(CHEMBL1084615 | CHEMBL565540 | 5-Morpholin-4-ylpen...)
Affinity DataEC50:  1.65E+3nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataEC50:  490nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in rat GH4C1 cells by whole cell patch-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319682(1-(6-(2-fluorophenyl)pyridin-3-yl)-3-(4-(piperidin...)
Affinity DataEC50:  150nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataEC50:  70nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Binding affinity to human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319676(1-(2'-fluorobiphenyl-4-yl)-3-(4-(piperidin-1-yl)bu...)
Affinity DataIC50: 5.70E+3nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319677(1-(4'-fluorobiphenyl-4-yl)-3-(4-(piperidin-1-yl)bu...)
Affinity DataIC50: 5.80E+3nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataIC50: 7.50E+3nMAssay Description:Binding affinity to adrenergic alpha2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319675(1-(2'-methoxybiphenyl-4-yl)-3-(4-(piperidin-1-yl)b...)
Affinity DataIC50: 7.80E+3nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319674(1-(biphenyl-4-yl)-3-(4-(piperidin-1-yl)butyl)urea ...)
Affinity DataIC50: 7.90E+3nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Agonist activity at alpha4beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319678(1-(4-(6-fluoropyridin-3-yl)phenyl)-3-(4-(piperidin...)
Affinity DataIC50: 3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319679(1-(4-Piperidin-1-ylbutyl)-3-(4-pyridin-2-ylphenyl)...)
Affinity DataIC50: 3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319680(1-(6-phenylpyridin-3-yl)-3-(4-(piperidin-1-yl)buty...)
Affinity DataIC50: 3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319681(1-(6-(2-methoxyphenyl)pyridin-3-yl)-3-(4-(piperidi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319682(1-(6-(2-fluorophenyl)pyridin-3-yl)-3-(4-(piperidin...)
Affinity DataIC50: 3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319683(1-(6'-fluoro-2,3'-bipyridin-5-yl)-3-(4-(piperidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319684(1-(2,2'-bipyridin-5-yl)-3-(4-(piperidin-1-yl)butyl...)
Affinity DataIC50: 3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataIC50: 3.50E+4nMAssay Description:Binding affinity to adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity to 5HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed