Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50031987
TargetGlycogen synthase kinase-3 beta(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889(3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50322830(N,8-diphenyl-9H-purin-6-amine | CHEMBL1210175)
Affinity DataIC50: 16nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50322829(3-(6-(phenylamino)-9H-purin-8-yl)benzonitrile | CH...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889(3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-...)
Affinity DataIC50: 35.0nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889(3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-...)
Affinity DataIC50: 36.3nMAssay Description:Inhibition of MAPKAPK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889(3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-...)
Affinity DataIC50: 49.0nMAssay Description:Inhibition of TYRO3/SKYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889(3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-...)
Affinity DataIC50: 102nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50322826(N-(8-(naphthalen-2-yl)-9H-purin-6-yl)cyclopropanec...)
Affinity DataIC50: 169nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50322828(N-(8-(3-chlorophenyl)-9H-purin-6-yl)cyclopropaneca...)
Affinity DataIC50: 365nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50322827(N-(8-(3-cyanophenyl)-9H-purin-6-yl)cyclopropanecar...)
Affinity DataIC50: 781nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50322825(N-(8-(3-cyanophenyl)-9H-purin-6-yl)pentanamide | C...)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889(3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-...)
Affinity DataIC50: 3.18E+3nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889(3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-...)
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of CK2alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889(3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-...)
Affinity DataIC50: 4.19E+3nMAssay Description:Inhibition of CK1alpha1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50059889(3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-...)
Affinity DataIC50: 5.09E+3nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM50322824(N-(8-(naphthalen-2-yl)-9H-purin-6-yl)pentanamide |...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed