Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50031883
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320968(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 160nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320969(Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxylic aci...)
Affinity DataIC50: 330nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320970(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 400nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320992(2-(5-Benzyl-1H-pyrazol-3-yl)-3-[(4-fluorobenzylami...)
Affinity DataIC50: 500nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320967(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 540nMAssay Description:Inhibition of GST-tagged full length GSK3-beta assessed as inhibition of ATP consumption after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320979(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 560nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320970(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 630nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320968(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 630nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320994(2-(5-Benzyl-1H-pyrazol-3-yl)-3-morpholin-4-ylmethy...)
Affinity DataIC50: 630nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320967(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 630nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320978(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 630nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320967(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 790nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320991(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 850nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320989(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320972(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320968(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of GST-tagged full length GSK3-beta assessed as inhibition of ATP consumption after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320977(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320987(2-(5-Benzyl-1H-pyrazol-3-yl)-3-hydroxymethyl-1Hind...)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320975(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320974(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320971(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320976(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320980(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320970(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of GST-tagged full length GSK3-beta assessed as inhibition of ATP consumption after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320973(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320981(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320969(Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxylic aci...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320984(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320983(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 4.36E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320988(2-(5-benzyl-1H-pyrazol-3-yl)-N-methyl-3-((pyridin-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320978(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320970(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 5.75E+3nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320969(Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxylic aci...)
Affinity DataIC50: 6.76E+3nMAssay Description:Inhibition of GST-tagged full length GSK3-beta assessed as inhibition of ATP consumption after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320967(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 7.08E+3nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320968(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 9.33E+3nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320982(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320969(Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxylic aci...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320989(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320989(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320990(3-[(4-Methoxy-benzylamino)-methyl]-2-(4-phenyl-1Hp...)
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320978(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320985(2-(5-Benzyl-1H-pyrazol-3-yl)-3-[(4-hydroxybutylami...)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320979(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320993(3-Hydroxymethyl-2-(4-phenyl-1H-pyrazol-3-yl)-1Hind...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320986(3-[(3-Hydroxy-propylamino)-methyl]-2-(4-phenyl-1Hp...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed