Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50031824
TargetMu-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 15nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50320022((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataIC50: 25nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50320024((S)-N-(3-((S)-1-amino-1-oxo-3-phenylpropan-2-ylami...)
Affinity DataIC50: 170nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50320023((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataIC50: 330nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50320022((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataIC50: 390nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically evoked contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 510nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically evoked contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50320023((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataIC50: 1.10E+3nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically evoked contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50320024((S)-N-(3-((S)-1-amino-1-oxo-3-phenylpropan-2-ylami...)
Affinity DataIC50: 1.90E+3nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically evoked contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50320022((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  9.60nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50320023((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50320024((S)-N-(3-((S)-1-amino-1-oxo-3-phenylpropan-2-ylami...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50320023((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataKi:  7.30E+3nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50320022((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed