Compile Data Set for Download or QSAR
Report error Found 139 Enz. Inhib. hit(s) with all data for entry = 50031834
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320214(3-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)pyr...)
Affinity DataIC50: 2nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320205(N-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320225(N-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320209(1-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 5nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320224(1-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 6nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320216(isobutyl4-(7-amino-3-(3-(piperazin-1-yl)phenyl)pyr...)
Affinity DataIC50: 7nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320218(isobutyl4-(7-amino-3-(3-(4-(2-aminoacetyl)piperazi...)
Affinity DataIC50: 7nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320204(3-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 8nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320214(3-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)pyr...)
Affinity DataIC50: 8nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320223(1-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 8nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320214(3-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)pyr...)
Affinity DataIC50: 8nMAssay Description:Inhibition of HCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320210(3-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 13nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320209(1-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 13nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320207(phenyl4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phen...)
Affinity DataIC50: 14nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320205(N-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 14nMAssay Description:Inhibition of HCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320224(1-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 16nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320222(phenyl4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phen...)
Affinity DataIC50: 16nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320209(1-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 21nMAssay Description:Inhibition of HCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320203(isobutyl4-(7-amino-3-(4-(4-methylpiperazin-1-yl)ph...)
Affinity DataIC50: 22nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320212(isobutyl4-(7-amino-3-(3-(4-methylpiperazin-1-yl)ph...)
Affinity DataIC50: 23nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320226(N-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 23nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320221(isobutyl4-(7-amino-3-(3-(4-methylpiperazin-1-yl)ph...)
Affinity DataIC50: 24nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320208(1-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 25nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320229(N-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 28nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320227(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)pyr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320223(1-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 31nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320225(N-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 33nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320228(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)pyr...)
Affinity DataIC50: 36nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320225(N-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 37nMAssay Description:Inhibition of HCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320207(phenyl4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phen...)
Affinity DataIC50: 37nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320219(isobutyl4-(7-amino-3-(4-(4-(2-methoxyethyl)piperaz...)
Affinity DataIC50: 37nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320203(isobutyl4-(7-amino-3-(4-(4-methylpiperazin-1-yl)ph...)
Affinity DataIC50: 40nMAssay Description:Inhibition of ABLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320221(isobutyl4-(7-amino-3-(3-(4-methylpiperazin-1-yl)ph...)
Affinity DataIC50: 63nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320224(1-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 70nMAssay Description:Inhibition of HCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320203(isobutyl4-(7-amino-3-(4-(4-methylpiperazin-1-yl)ph...)
Affinity DataIC50: 74nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320206(N-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 75nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320205(N-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 76nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320228(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)pyr...)
Affinity DataIC50: 85nMAssay Description:Inhibition of HCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320207(phenyl4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phen...)
Affinity DataIC50: 88nMAssay Description:Inhibition of HCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320203(isobutyl4-(7-amino-3-(4-(4-methylpiperazin-1-yl)ph...)
Affinity DataIC50: 89nMAssay Description:Inhibition of cKItMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320208(1-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 92nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320214(3-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)pyr...)
Affinity DataIC50: 96nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320206(N-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 106nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320203(isobutyl4-(7-amino-3-(4-(4-methylpiperazin-1-yl)ph...)
Affinity DataIC50: 107nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320204(3-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 110nMAssay Description:Inhibition of HCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320211(isobutyl4-(7-amino-5-methyl-3-(3-(4-methylpiperazi...)
Affinity DataIC50: 116nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320210(3-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 128nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320224(1-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 130nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320225(N-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)...)
Affinity DataIC50: 135nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50320222(phenyl4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phen...)
Affinity DataIC50: 140nMAssay Description:Inhibition of LCK in human Jurkat cells assessed as ZAP70 phosphorylation by FACS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
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