Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50031971
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322476((2S)-5-(4-tert-butylphenylamino)-2-((4R)-4-((3R,7R...)
Affinity DataKi:  275nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322507((2S)-5-(3-tert-butylphenylamino)-2-((4R)-4-((3R,7R...)
Affinity DataKi:  587nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322501((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  889nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322480((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322498((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  1.25E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322474((S)-5-(4-chlorophenylamino)-2-((R)-4-((3R,5R,7R,8R...)
Affinity DataKi:  1.91E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322473((S)-2-((R)-4-((3R,5R,7R,8R,9S,10S,13R,14S,17R)-3,7...)
Affinity DataKi:  2.01E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322475((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  2.02E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322491(3-((S)-5-(benzylperoxy)-4-((R)-4-((3R,5R,7R,8R,9S,...)
Affinity DataKi:  2.24E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322477((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322497((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  2.31E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322500((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  2.63E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322484((2S)-5-(2-aminophenylamino)-2-((4R)-4-((3R,7R,8R,9...)
Affinity DataKi:  2.64E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322499((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  3.02E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322487((2S)-5-(2,4-difluorophenylamino)-2-((4R)-4-((3R,7R...)
Affinity DataKi:  3.16E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322502((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322503((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  3.89E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322506((2S)-5-(2-tert-butylphenylamino)-2-((4R)-4-((3R,7R...)
Affinity DataKi:  3.93E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322479((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  4.03E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322504((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  4.22E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322489((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322481((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  5.16E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322490((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  5.19E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322483((2S)-5-(4-(tert-butoxycarbonylamino)phenylamino)-2...)
Affinity DataKi:  5.26E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322505((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  6.09E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322482((2S)-5-(3-(tert-butoxycarbonylamino)phenylamino)-2...)
Affinity DataKi:  6.53E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322478((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  7.65E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322488((2S)-2-((4R)-4-((3R,7R,8R,9S,10S,13R,14S,17R)-3,7-...)
Affinity DataKi:  8.07E+3nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322486((2S)-5-(4-aminophenylamino)-2-((4R)-4-((3R,7R,8R,9...)
Affinity DataKi:  1.59E+4nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322485((2S)-5-(3-aminophenylamino)-2-((4R)-4-((3R,7R,8R,9...)
Affinity DataKi:  1.63E+4nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322493(3-((4S)-4-carboxylato-4-((4R)-4-((3R,7R,8R,9S,10S,...)
Affinity DataKi:  3.59E+4nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322492(2-((S)-4-carboxy-4-((R)-4-((3R,5R,7R,8R,9S,10S,13R...)
Affinity DataKi:  4.04E+4nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322496(4-(((4S)-4-carboxylato-4-((4R)-4-((3R,7R,8R,9S,10S...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322494(4-((4S)-4-carboxylato-4-((4R)-4-((3R,7R,8R,9S,10S,...)
Affinity DataKi:  1.08E+5nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50322495(3-(((4S)-4-carboxylato-4-((4R)-4-((3R,7R,8R,9S,10S...)
Affinity DataKi:  1.26E+5nMAssay Description:Inhibition of human ASBT expressed in MDCK cells assessed as inhibition of [3H]taurocholic acid uptake after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed