Compile Data Set for Download or QSAR
Report error Found 112 Enz. Inhib. hit(s) with all data for entry = 50031846
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM11885(N-hydroxy-4-{[4-(phenylsulfanyl)benzene]sulfonyl}-...)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM11885(N-hydroxy-4-{[4-(phenylsulfanyl)benzene]sulfonyl}-...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320412(N-hydroxy-4-(4-(4-(4-(trifluoromethyl)phenyl)piper...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320410(N-hydroxy-4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)...)
Affinity DataIC50: 0.630nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320393(4-(4-(4-(4-chlorophenyl)piperidin-1-yl)phenylsulfo...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320413(4-(4-(4-(4-chlorophenyl)piperazin-1-yl)phenylsulfo...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM11885(N-hydroxy-4-{[4-(phenylsulfanyl)benzene]sulfonyl}-...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320405(N-hydroxy-4-(4-(4-phenylpiperazin-1-yl)phenylsulfo...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM11885(N-hydroxy-4-{[4-(phenylsulfanyl)benzene]sulfonyl}-...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320411(N-hydroxy-4-(4-(4-p-tolylpiperazin-1-yl)phenylsulf...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320393(4-(4-(4-(4-chlorophenyl)piperidin-1-yl)phenylsulfo...)
Affinity DataIC50: 2nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320390(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-(trifluoromethy...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320406(4-(4-(4-(2-fluorophenyl)piperazin-1-yl)phenylsulfo...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320389(1-cyclopropyl-N-hydroxy-4-(4-(4-phenylpiperazin-1-...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320413(4-(4-(4-(4-chlorophenyl)piperazin-1-yl)phenylsulfo...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320391(N-hydroxy-4-(4-(4-phenylpiperidin-1-yl)phenylsulfo...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320389(1-cyclopropyl-N-hydroxy-4-(4-(4-phenylpiperazin-1-...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320391(N-hydroxy-4-(4-(4-phenylpiperidin-1-yl)phenylsulfo...)
Affinity DataIC50: 6nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320401(N-hydroxy-4-(4-(4-(4-methoxy-2-methylphenyl)piperi...)
Affinity DataIC50: 7nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320407(N-hydroxy-4-(4-(4-o-tolylpiperazin-1-yl)phenylsulf...)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320409(N-hydroxy-4-(4-(4-(3-methoxyphenyl)piperazin-1-yl)...)
Affinity DataIC50: 8nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320408(4-(4-(4-(2-chlorophenyl)piperazin-1-yl)phenylsulfo...)
Affinity DataIC50: 9nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320398(N-hydroxy-4-(4-(4-(2-hydroxyphenyl)piperidin-1-yl)...)
Affinity DataIC50: 11nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320400(N-hydroxy-4-(4-(4-(naphthalen-1-yl)piperidin-1-yl)...)
Affinity DataIC50: 11nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320402(4-(4-(4-(2,4-dimethoxyphenyl)piperidin-1-yl)phenyl...)
Affinity DataIC50: 11nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320403(4-(4-(4-(2,5-dimethoxyphenyl)piperidin-1-yl)phenyl...)
Affinity DataIC50: 11nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320412(N-hydroxy-4-(4-(4-(4-(trifluoromethyl)phenyl)piper...)
Affinity DataIC50: 12nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM11885(N-hydroxy-4-{[4-(phenylsulfanyl)benzene]sulfonyl}-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320392(N-hydroxy-4-(4-(4-(2-methoxyphenyl)piperidin-1-yl)...)
Affinity DataIC50: 18nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320410(N-hydroxy-4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)...)
Affinity DataIC50: 18nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM11885(N-hydroxy-4-{[4-(phenylsulfanyl)benzene]sulfonyl}-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320417(N-hydroxy-4-(4-(4-(3-(trifluoromethyl)phenyl)piper...)
Affinity DataIC50: 20nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320406(4-(4-(4-(2-fluorophenyl)piperazin-1-yl)phenylsulfo...)
Affinity DataIC50: 21nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320405(N-hydroxy-4-(4-(4-phenylpiperazin-1-yl)phenylsulfo...)
Affinity DataIC50: 24nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50: 25nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320396(N-hydroxy-4-(4-(4-(2-(trifluoromethyl)phenyl)piper...)
Affinity DataIC50: 29nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320418(4-(4-(4-(2,4-dimethylphenyl)piperazin-1-yl)phenyls...)
Affinity DataIC50: 29nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320395(N-hydroxy-4-(4-(4-o-tolylpiperidin-1-yl)phenylsulf...)
Affinity DataIC50: 33nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320390(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-(trifluoromethy...)
Affinity DataIC50: 33nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320399(4-(4-(4-(4'-fluorobiphenyl-2-yl)piperidin-1-yl)phe...)
Affinity DataIC50: 34nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320397(4-(4-(4-(2-ethoxyphenyl)piperidin-1-yl)phenylsulfo...)
Affinity DataIC50: 35nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320411(N-hydroxy-4-(4-(4-p-tolylpiperazin-1-yl)phenylsulf...)
Affinity DataIC50: 35nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320408(4-(4-(4-(2-chlorophenyl)piperazin-1-yl)phenylsulfo...)
Affinity DataIC50: 40nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320394(4-(4-(4-(2-chlorophenyl)piperidin-1-yl)phenylsulfo...)
Affinity DataIC50: 43nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320409(N-hydroxy-4-(4-(4-(3-methoxyphenyl)piperazin-1-yl)...)
Affinity DataIC50: 49nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50: 59nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320404(N-hydroxy-4-(4-(4-(5-isopropyl-2-methoxyphenyl)pip...)
Affinity DataIC50: 70nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320398(N-hydroxy-4-(4-(4-(2-hydroxyphenyl)piperidin-1-yl)...)
Affinity DataIC50: 70nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
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