Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50039170
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318690(4-Piperidinyl-1,2,5-thiadiazolyl-3-morpholine carb...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318691(4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl piperidin...)
Affinity DataIC50: 152nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318686(4-(Azepan-1-yl)-1,2,5-thiadiazol-3-yl morpholine-4...)
Affinity DataIC50: 189nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318687(4-(Azepan-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318689(4-Morpholino-1,2,5-thiadiazol-3-yl piperidine-1-ca...)
Affinity DataIC50: 424nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318692(4-(Pyrrolidin-1-yl)-1,2,5-thiadiazol-3-yl morpholi...)
Affinity DataIC50: 473nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318688(CHEMBL1082518 | cid_655946 | 3-N-Morpholinocarbama...)
Affinity DataIC50: 492nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318693(4-(Pyrrolidin-1-yl)-1,2,5-thiadiazol-3-yl Piperidi...)
Affinity DataIC50: 496nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed