Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50039292
TargetDihydrofolate reductase(Lactobacillus casei)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Lactobacillus casei DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326679(4-(2-(4-((2,4-Diaminopteridin-6-yl)methylamino)ben...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Lactobacillus casei DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326680(4-((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Lactobacillus casei DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326675(4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Lactobacillus casei DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326674(4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Lactobacillus casei DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326678(4-((2,4-Diaminopteridin-6-yl)methylamino)-N-(4-sul...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Lactobacillus casei DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326674(4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326678(4-((2,4-Diaminopteridin-6-yl)methylamino)-N-(4-sul...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326680(4-((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)...)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326674(4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326676(4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM11635(4-sulfamoyl-N-[2-(4-sulfamoylphenyl)ethyl]benzamid...)
Affinity DataKi:  5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 9(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM11635(4-sulfamoyl-N-[2-(4-sulfamoylphenyl)ethyl]benzamid...)
Affinity DataKi:  18nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM11635(4-sulfamoyl-N-[2-(4-sulfamoylphenyl)ethyl]benzamid...)
Affinity DataKi:  40nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326676(4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...)
Affinity DataKi:  45nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  250nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326680(4-((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)...)
Affinity DataKi:  260nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326675(4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...)
Affinity DataKi:  350nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326678(4-((2,4-Diaminopteridin-6-yl)methylamino)-N-(4-sul...)
Affinity DataKi:  920nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326675(4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326677(4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326679(4-(2-(4-((2,4-Diaminopteridin-6-yl)methylamino)ben...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326674(4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326680(4-((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)...)
Affinity DataKi:  1.29E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326675(4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesu...)
Affinity DataKi:  2.17E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326678(4-((2,4-Diaminopteridin-6-yl)methylamino)-N-(4-sul...)
Affinity DataKi:  3.56E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326677(4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...)
Affinity DataKi:  8.17E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326677(4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...)
Affinity DataKi:  2.64E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326676(4-(2-((2,4-Diaminopteridin-6-yl)methylamino)ethyl)...)
Affinity DataKi:  2.74E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326679(4-(2-(4-((2,4-Diaminopteridin-6-yl)methylamino)ben...)
Affinity DataKi:  3.64E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50326679(4-(2-(4-((2,4-Diaminopteridin-6-yl)methylamino)ben...)
Affinity DataKi:  3.71E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed