Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50039236
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322299(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-(3-piper...)
Affinity DataIC50: 3.60nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50320821(N-{4-[3-(beta-Alanylamino)phenyl]-3-cyano-6-(4-flu...)
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322292(N-{3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-(glyc...)
Affinity DataIC50: 4.10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322307(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-m...)
Affinity DataIC50: 4.60nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322300(N-{3-Cyano-4-[3-(1,4-diazepan-1-yl)phenyl]-6-(4-fl...)
Affinity DataIC50: 7.30nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50320810(N-(4-(3-(3-aminopropanamido)phenyl)-3-cyano-6-(4-f...)
Affinity DataIC50: 7.40nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322309(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-(3-{[(2S...)
Affinity DataIC50: 7.90nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322313(rac-N-[3-Cyano-4-(3-{[3-(ethylamino)pentanoyl]amin...)
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322293(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-m...)
Affinity DataIC50: 8.40nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322319(rac-N-{3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-(...)
Affinity DataIC50: 9.70nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322303(N-{3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-(pipe...)
Affinity DataIC50: 9.70nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322318(rac-N-[3-Cyano-4-(3-{[3-(ethylamino)butanoyl]amino...)
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322310(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-(3-{[(2R...)
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322316(N-[3-Cyano-4-{3-[(N-ethyl-N-methyl-beta-alanyl)ami...)
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322308(N-[3-Cyano-4-{3-[(N,N-dimethyl-beta-alanyl)amino]p...)
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322302(N-{3-Cyano-4-[3-(4-ethylpiperazin-1-yl)phenyl]-6-(...)
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322295(N-[3-Cyano-4-{3-[(N,N-dimethylglycyl)amino]phenyl}...)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322289(rac-N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[...)
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322301(N-{3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-(4-me...)
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322299(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-(3-piper...)
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322297(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(pyr...)
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322294(N-(3-{3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-2-[(fur...)
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322317(N-[3-Cyano-4-{3-[(N,N-diethyl-beta-alanyl)amino]ph...)
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322312(rac-N-[3-Cyano-4-(3-{[3-(diethylamino)butanoyl]ami...)
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322290(N-{3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-({[(2...)
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322311(rac-N-[3-Cyano-4-(3-{[3-(dimethylamino)butanoyl]am...)
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322305(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(4-m...)
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322291(N-[3-Cyano-4-(3-{[2-(dimethylamino)ethyl]carbamoyl...)
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322306(N-[3-Cyano-4-{3-[(4-ethylpiperazin-1-yl)methyl]phe...)
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322307(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-m...)
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322314(rac-N-[3-Cyano-4-(3-{[3-(diethylamino)pentanoyl]am...)
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322304(N-{3-Cyano-4-[3-(1,4-diazepan-1-ylmethyl)phenyl]-6...)
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322309(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-(3-{[(2S...)
Affinity DataIC50: 26nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322293(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-m...)
Affinity DataIC50: 26nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322296(N-[3-Cyano-4-{3-[(N,N-diethylglycyl)amino]phenyl}-...)
Affinity DataIC50: 30nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322298(N-[3-Cyano-4-(3-{[2-(dimethylamino)ethyl](methyl)a...)
Affinity DataIC50: 30nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322310(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-(3-{[(2R...)
Affinity DataIC50: 38nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322302(N-{3-Cyano-4-[3-(4-ethylpiperazin-1-yl)phenyl]-6-(...)
Affinity DataIC50: 47nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322308(N-[3-Cyano-4-{3-[(N,N-dimethyl-beta-alanyl)amino]p...)
Affinity DataIC50: 47nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322295(N-[3-Cyano-4-{3-[(N,N-dimethylglycyl)amino]phenyl}...)
Affinity DataIC50: 130nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322315(N-(3-cyano-4-(3-(2-(dimethylamino)acetamido)phenyl...)
Affinity DataIC50: 180nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322299(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-(3-piper...)
Affinity DataIC50: 930nMAssay Description:Antagonist activity at human GPR54 receptor assessed as inhibition of metastin-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed