Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 50032064
TargetHistone-lysine N-methyltransferase EHMT1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50: 15nMAssay Description:Activity at methyl transferase activity GLP by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300041(7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl...)
Affinity DataKd:  23nMAssay Description:Binding affinity to G9a by isothermal titration colorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50: 23nMAssay Description:Activity at methyl transferase activity GLP by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 27nMAssay Description:Activity at methyl transferase activity GLP by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 34nMAssay Description:Activity at methyl transferase activity GLP by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300041(7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl...)
Affinity DataIC50: 50nMAssay Description:Activity at methyl transferase activity GLP by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300041(7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl...)
Affinity DataIC50: 58nMAssay Description:Activity at methyl transferase activity GLP by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataKd:  130nMAssay Description:Binding affinity to G9a by isothermal titration colorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323808(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...)
Affinity DataIC50: 8.00E+3nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50: 9.00E+3nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323808(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323809(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323809(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...)
Affinity DataIC50: 2.50E+4nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300041(7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl...)
Affinity DataIC50: 4.00E+4nMAssay Description:Activity at methyl transferase activity SET8/preSet7 by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Activity at methyl transferase activity SET8/preSet7 by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300041(7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl...)
Affinity DataIC50: 4.00E+4nMAssay Description:Activity at methyl transferase activity PRMT3 by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300041(7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl...)
Affinity DataIC50: 4.00E+4nMAssay Description:Activity at methyl transferase activity SET7/9 by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Activity at methyl transferase activity PRMT3 by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Activity at methyl transferase activity SET7/9 by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323805(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-7-(3-(met...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300041(7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl...)
Affinity DataIC50: 4.30E+4nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323807(6-Methoxy-7-(3-(methyl(propyl)amino)propoxy)-2-(4-...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323803(7-(5-(Dimethylamino)pentyloxy)-6-methoxy-2-(4-meth...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323807(6-Methoxy-7-(3-(methyl(propyl)amino)propoxy)-2-(4-...)
Affinity DataIC50: 5.10E+4nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323806(7-(3-(Diethylamino)propoxy)-6-methoxy-2-(4-methyl-...)
Affinity DataIC50: 5.20E+4nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300041(7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323814(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...)
Affinity DataIC50: 5.70E+4nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323806(7-(3-(Diethylamino)propoxy)-6-methoxy-2-(4-methyl-...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323803(7-(5-(Dimethylamino)pentyloxy)-6-methoxy-2-(4-meth...)
Affinity DataIC50: 9.50E+4nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323814(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323801(7-(2-(Dimethylamino)ethoxy)-6-methoxy-2-(4-methyl-...)
Affinity DataIC50: 1.10E+5nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323812(7-(5-Aminopentyloxy)-6-methoxy-2-(4-methyl-1,4-dia...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323802(7-(4-(Dimethylamino)butoxy)-6-methoxy-2-(4-methyl-...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323801(7-(2-(Dimethylamino)ethoxy)-6-methoxy-2-(4-methyl-...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323805(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-7-(3-(met...)
Affinity DataIC50: 1.20E+5nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323802(7-(4-(Dimethylamino)butoxy)-6-methoxy-2-(4-methyl-...)
Affinity DataIC50: 1.40E+5nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300030(6,7-dimethoxy-2-(4-methylpiperazin-1-yl)-N-(1-meth...)
Affinity DataIC50: 1.50E+5nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323815(N1-(2-(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-...)
Affinity DataIC50: 1.73E+5nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 1.80E+5nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300030(6,7-dimethoxy-2-(4-methylpiperazin-1-yl)-N-(1-meth...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300029(6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-...)
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323812(7-(5-Aminopentyloxy)-6-methoxy-2-(4-methyl-1,4-dia...)
Affinity DataIC50: 2.35E+5nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300029(6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-...)
Affinity DataIC50: 3.30E+5nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323815(N1-(2-(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-...)
Affinity DataIC50: 3.45E+5nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300031(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...)
Affinity DataIC50: 5.10E+5nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300031(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...)
Affinity DataIC50: 5.50E+5nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323810(6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-meth...)
Affinity DataIC50: 7.80E+5nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50300032(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...)
Affinity DataIC50: 8.10E+5nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
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