Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50035962
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012229(CHEMBL555543 | 5-Thiomorpholin-4-ylmethyl-thieno[2...)
Affinity DataKi:  0.440nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012211(CHEMBL544738 | 5-{[Bis-(2-methoxy-ethyl)-amino]-me...)
Affinity DataKi:  0.950nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012231(CHEMBL540026 | 5-Morpholin-4-ylmethyl-thieno[2,3-b...)
Affinity DataKi:  1nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012209(CHEMBL554425 | 5-{[Bis-(2-methoxy-ethyl)-amino]-me...)
Affinity DataKi:  1.34nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012227(CHEMBL542122 | 5-{[Bis-(1-methyl-2-oxo-ethyl)-amin...)
Affinity DataKi:  1.49nMAssay Description:The compound was tested for in vitro binding affinity against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012208(CHEMBL543319 | 5-{1-[[2-(2-Methoxy-ethoxy)-ethyl]-...)
Affinity DataKi:  1.54nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012207(CHEMBL543559 | 5-{[[2-(2-Methoxy-ethoxy)-ethyl]-(2...)
Affinity DataKi:  1.58nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012225(CHEMBL544032 | 5-[(2-Fluoro-ethylamino)-methyl]-th...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012232(CHEMBL544970 | 5-[(2-Methylsulfanyl-ethylamino)-me...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012217(CHEMBL53964 | 5-Sulfamoyl-thieno[2,3-b]thiophene-2...)
Affinity DataKi:  2.39nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012215(CHEMBL554042 | 5-{[Bis-(2-hydroxy-ethyl)-amino]-me...)
Affinity DataKi:  2.60nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012220(CHEMBL543792 | 5-(Isobutylamino-methyl)-thieno[3,2...)
Affinity DataKi:  2.70nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012236(CHEMBL555548 | 5-({Bis-[2-(2-methoxy-ethoxy)-ethyl...)
Affinity DataKi:  2.77nMAssay Description:The compound was tested for in vitro binding affinity against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012221(CHEMBL553832 | 5-{1-[2-(2-Methoxy-ethoxy)-ethylami...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012219(CHEMBL556132 | 5-[(2-Methoxy-ethylamino)-methyl]-t...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012226(CHEMBL52944 | 5-(1-Oxo-1lambda*4*-thiomorpholin-4-...)
Affinity DataKi:  3.40nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012210(CHEMBL51975 | 5-Sulfamoyl-thieno[2,3-b]thiophene-2...)
Affinity DataKi:  3.40nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012213(CHEMBL544030 | 5-[(2-Methoxy-ethylamino)-methyl]-t...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012233(CHEMBL544731 | 5-Sulfamoyl-thieno[2,3-b]thiophene-...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012218(CHEMBL538245 | 5-(Isobutylamino-methyl)-thieno[2,3...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012224(CHEMBL539258 | 5-[(2-Methanesulfonyl-ethylamino)-m...)
Affinity DataKi:  4.80nMAssay Description:The compound was tested for in vitro binding affinity against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012234(CHEMBL545431 | 5-Sulfamoyl-thieno[2,3-b]thiophene-...)
Affinity DataKi:  6nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012235(CHEMBL553217 | 5-[(2-Methanesulfinyl-ethylamino)-m...)
Affinity DataKi:  6nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012230(CHEMBL553951 | 5-[(Cyclopropylmethyl-amino)-methyl...)
Affinity DataKi:  7nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012223(CHEMBL50395 | 5-{2-(4-Fluoro-phenyl)-1-[[2-(2-meth...)
Affinity DataKi:  7nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012214(CHEMBL51097 | 5-Sulfamoyl-thieno[2,3-b]thiophene-2...)
Affinity DataKi:  9nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012216(CHEMBL555889 | 5-Sulfamoyl-thieno[2,3-b]thiophene-...)
Affinity DataKi:  11nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012222(CHEMBL552892 | 5-Methylaminomethyl-thieno[3,2-b]th...)
Affinity DataKi:  12nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012212(CHEMBL555385 | 5-Methylaminomethyl-thieno[2,3-b]th...)
Affinity DataKi:  21nMAssay Description:The compound was tested for in vitro binding affinity against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50012228(CHEMBL539259 | 5-(tert-Butylamino-methyl)-thieno[2...)
Affinity DataKi:  37nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed