Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50032075
TargetMetabotropic glutamate receptor 5(Rat)
Eth Zurich (Swiss Federal Institute of Technology)

Curated by ChEMBL
LigandPNGBDBM50323923((E)-3-((2-(Fluoromethyl)thiazol-4-yl)ethynyl)cyclo...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Eth Zurich (Swiss Federal Institute of Technology)

Curated by ChEMBL
LigandPNGBDBM50323924((E)-3-(Thiazol-2-ylethynyl)cyclohex-2-enone O-meth...)
Affinity DataKi:  20.3nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Eth Zurich (Swiss Federal Institute of Technology)

Curated by ChEMBL
LigandPNGBDBM50323926((E)-3-((2-Methylthiazol-4-yl)ethynyl)cyclohex-2-en...)
Affinity DataKi:  21.9nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Eth Zurich (Swiss Federal Institute of Technology)

Curated by ChEMBL
LigandPNGBDBM50323925((E)-3-(Thiazol-4-ylethynyl)cyclohex-2-enone O-2-(2...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed