Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50032151
TargetEstrogen receptor(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at human wild type ERalpha expressed in HEK293T cells co-expressing ERE assessed as inhibition of estradiol-induced transactivati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 6.90nMAssay Description:Antagonist activity at human wild type ERbeta expressed in HEK293T cells co-expressing ERE assessed as inhibition of estradiol-induced transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50324966(3-(2-(4-hydroxyphenyl)-3-(4-(2-(piperidin-1-yl)eth...)
Affinity DataIC50: 82nMAssay Description:Antagonist activity at human wild type ERalpha expressed in HEK293T cells co-expressing ERE assessed as inhibition of estradiol-induced transactivati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50324966(3-(2-(4-hydroxyphenyl)-3-(4-(2-(piperidin-1-yl)eth...)
Affinity DataIC50: 104nMAssay Description:Antagonist activity at human wild type ERbeta expressed in human HeLa cells co-expressing AP-1 assessed as inhibition of raloxifene-induced transacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50324966(3-(2-(4-hydroxyphenyl)-3-(4-(2-(piperidin-1-yl)eth...)
Affinity DataEC50:  150nMAssay Description:Antagonist activity at human wild type ERbeta expressed in human HeLa cells co-expressing AP-1 assessed as inhibition of transactivation activity by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Delaware

Curated by ChEMBL
LigandPNGBDBM50324966(3-(2-(4-hydroxyphenyl)-3-(4-(2-(piperidin-1-yl)eth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human wild type ERbeta expressed in HEK293T cells co-expressing ERE assessed as inhibition of estradiol-induced transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed