Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50035966
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012250(CHEMBL58947 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50282993((2S,4R)-4-Cyclohexyl-2-hydroxy-3-((R)-3-methylsulf...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012251(CHEMBL292677 | 2-{2-(1-Cyclohexylmethyl-2,3-dihydr...)
Affinity DataIC50: 0.230nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 0.280nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012249(CHEMBL58256 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 0.680nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006202(A-64662 | CHEMBL300337 | 3-Amino-N-[1-[1-(1-cycloh...)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012257(CHEMBL299252 | N-[1-Cyclohexylmethyl-3,3-difluoro-...)
Affinity DataIC50: 0.790nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM17941((2S,4S,5S)-5-[(2S)-2-[(2S)-2-benzyl-3-[(2-methylpr...)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012252(CHEMBL57492 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 0.950nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012247(CHEMBL291719 | 4-(1-Cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012255(CHEMBL293328 | N-[1-Cyclohexylmethyl-2-hydroxy-3-(...)
Affinity DataIC50: 4nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012253(CHEMBL56982 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50282993((2S,4R)-4-Cyclohexyl-2-hydroxy-3-((R)-3-methylsulf...)
Affinity DataIC50: 24nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012250(CHEMBL58947 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012254(CHEMBL60535 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012247(CHEMBL291719 | 4-(1-Cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 36nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 36nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012249(CHEMBL58256 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 43nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012252(CHEMBL57492 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012253(CHEMBL56982 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012256(CHEMBL431751 | N-{1-[1-Hydroxy-2-(2-morpholin-4-yl...)
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012254(CHEMBL60535 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: 310nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012257(CHEMBL299252 | N-[1-Cyclohexylmethyl-3,3-difluoro-...)
Affinity DataIC50: 515nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012255(CHEMBL293328 | N-[1-Cyclohexylmethyl-2-hydroxy-3-(...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006202(A-64662 | CHEMBL300337 | 3-Amino-N-[1-[1-(1-cycloh...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012256(CHEMBL431751 | N-{1-[1-Hydroxy-2-(2-morpholin-4-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM17941((2S,4S,5S)-5-[(2S)-2-[(2S)-2-benzyl-3-[(2-methylpr...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012251(CHEMBL292677 | 2-{2-(1-Cyclohexylmethyl-2,3-dihydr...)
Affinity DataIC50: 5.18E+4nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed