Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50032106
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Human)
University of Piemonte Orientale Amedeo Avogadro

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)
Affinity DataIC50: 910nMAssay Description:Inhibition of human recombinant MBP-KAT2 expressed in HEK293 cells assessed as conversion of L-kynurenine to kynurenic acid after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Rat)
University of Piemonte Orientale Amedeo Avogadro

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat brain KAT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Human)
University of Piemonte Orientale Amedeo Avogadro

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KAT2 in human prefrontal cortex homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Human)
University of Piemonte Orientale Amedeo Avogadro

Curated by ChEMBL
LigandPNGBDBM50416560(CHEMBL1215660)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant MBP-KAT2 expressed in HEK293 cells assessed as conversion of L-kynurenine to kynurenic acid after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetKynurenine--oxoglutarate transaminase 1(Human)
University of Piemonte Orientale Amedeo Avogadro

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of KAT1 in human prefrontal cortex homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetKynurenine--oxoglutarate transaminase 1(Human)
University of Piemonte Orientale Amedeo Avogadro

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant MBP-KAT1 expressed in HEK293 cells assessed as conversion of L-kynurenine to kynurenic acid after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed