Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50032410
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328774(2-(3-(3-cyclopentyl-5-(3-(2,3-dichlorophenyl)ureid...)
Affinity DataIC50: 5nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328768(1-(5-tert-Butyl-2-{4-[2-(1,1-dioxo-1lambda6-thiomo...)
Affinity DataIC50: 7nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328755(2-(3-(3-tert-butyl-5-(3-(2,3-dichlorophenyl)ureido...)
Affinity DataIC50: 9nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328774(2-(3-(3-cyclopentyl-5-(3-(2,3-dichlorophenyl)ureid...)
Affinity DataIC50: 10nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328755(2-(3-(3-tert-butyl-5-(3-(2,3-dichlorophenyl)ureido...)
Affinity DataIC50: 11nMAssay Description:Inhibition of CRAFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328755(2-(3-(3-tert-butyl-5-(3-(2,3-dichlorophenyl)ureido...)
Affinity DataIC50: 11nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328773(2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(thiophen...)
Affinity DataIC50: 15nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328769(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-...)
Affinity DataIC50: 16nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328755(2-(3-(3-tert-butyl-5-(3-(2,3-dichlorophenyl)ureido...)
Affinity DataIC50: 17nMAssay Description:Inhibition of BRAFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328769(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-...)
Affinity DataIC50: 22nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328771(2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(2-fluoro...)
Affinity DataIC50: 25nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328766(1-(3-tert-butyl-1-(4-(hydroxymethyl)phenyl)-1H-pyr...)
Affinity DataIC50: 27nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328773(2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(thiophen...)
Affinity DataIC50: 28nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328771(2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(2-fluoro...)
Affinity DataIC50: 40nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328762(1-(3-tert-butyl-1-(3-(2-morpholino-2-oxoethyl)phen...)
Affinity DataIC50: 48nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328772(2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(thiophen...)
Affinity DataIC50: 48nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328767(3-(4-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327187(1-{5-tert-Butyl-2-[3-(1,1,3-trioxo-1lambda*6*-[1,2...)
Affinity DataIC50: 57nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328772(2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(thiophen...)
Affinity DataIC50: 66nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328763(2-(3-(3-tert-butyl-5-(3-(4-chlorophenyl)ureido)-1H...)
Affinity DataIC50: 68nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328770(2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-phenyl-1H...)
Affinity DataIC50: 79nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328755(2-(3-(3-tert-butyl-5-(3-(2,3-dichlorophenyl)ureido...)
Affinity DataIC50: 82nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328770(2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-phenyl-1H...)
Affinity DataIC50: 119nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328756(1-(3-tert-butyl-1-(3-((1-methyl-3,5-dioxo-1,2,4-tr...)
Affinity DataIC50: 292nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328757(1-(3-tert-butyl-1-(3-((4,4-dimethyl-3,5-dioxopyraz...)
Affinity DataIC50: 384nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328759(1-(1-(3-(2-aminoethyl)phenyl)-3-tert-butyl-1H-pyra...)
Affinity DataIC50: 508nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328760(3-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyr...)
Affinity DataIC50: 949nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328758(N-(N-(3-(3-tert-butyl-5-(3-(4-chlorophenyl)ureido)...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328765(1-(1-(4-(aminomethyl)phenyl)-3-tert-butyl-1H-pyraz...)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328764(1-{5-tert-Butyl-2-[4-(1,1-dioxo-1lambda*6*-thiomor...)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328772(2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(thiophen...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of p38alpha autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328761((S)-1-(3-tert-butyl-1-(3-(2-oxo-4-phenyloxazolidin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328772(2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(thiophen...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed