Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50032519
TargetPurine nucleoside phosphorylase(Human)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50195587(CHEMBL218291 | CHEMBL1213652 | 1,4-DIDEOXY-4-AZA-1...)
Affinity DataKd:  0.0560nMAssay Description:Inhibition of human PNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50195587(CHEMBL218291 | CHEMBL1213652 | 1,4-DIDEOXY-4-AZA-1...)
Affinity DataKi:  0.860nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUridine phosphorylase 1(Human)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330391(5-(3-(benzyloxy)benzyl)-1-((2-hydroxyethoxy)methyl...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human uridine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330391(5-(3-(benzyloxy)benzyl)-1-((2-hydroxyethoxy)methyl...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330390(5'-methylthio-immucillin-H | CHEMBL1275659)
Affinity DataKi:  2.70nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330392(CHEMBL1275660 | Immucillins, 15 | 7-(pyrrolidin-1-...)
Affinity DataKd:  5.5nMAssay Description:Inhibition of human PNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330390(5'-methylthio-immucillin-H | CHEMBL1275659)
Affinity DataKi:  303nMAssay Description:Inhibition of human PNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetUridine phosphorylase 1(Human)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50078082(5-(3-Benzyloxy-benzyl)-pyrimidine-2,4,6-trione | C...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of human uridine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330388(3-((2-Pyrrolidine-1-yl)-ethyl)uracil | CHEMBL12757...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330394(1-((2-Pyrrolidine-1-yl)-ethyl)uracil | CHEMBL12756...)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330388(3-((2-Pyrrolidine-1-yl)-ethyl)uracil | CHEMBL12757...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330395(1-((3-Pyrrolidine-1-yl)-propyl)uracil | CHEMBL1275...)
Affinity DataKi:  5.90E+4nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330389(3-((2-(l-Prolinol)-1-yl)-ethyl)uracil | CHEMBL1275...)
Affinity DataKi:  7.50E+4nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330397(1-((4-Pyrrolidine-1-yl)-butyl)uracil | CHEMBL12757...)
Affinity DataKi:  1.05E+5nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330398(1-((4-(l-Prolinol)-1-yl)-butyl)uracil | CHEMBL1275...)
Affinity DataKi:  1.13E+5nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330396(1-((3-(l-Prolinol)-1-yl)-propyl)uracil | CHEMBL127...)
Affinity DataKi:  1.36E+5nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330394(1-((2-Pyrrolidine-1-yl)-ethyl)uracil | CHEMBL12756...)
Affinity DataIC50: 1.41E+5nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330395(1-((3-Pyrrolidine-1-yl)-propyl)uracil | CHEMBL1275...)
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330389(3-((2-(l-Prolinol)-1-yl)-ethyl)uracil | CHEMBL1275...)
Affinity DataIC50: 3.66E+5nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330397(1-((4-Pyrrolidine-1-yl)-butyl)uracil | CHEMBL12757...)
Affinity DataIC50: 5.24E+5nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330398(1-((4-(l-Prolinol)-1-yl)-butyl)uracil | CHEMBL1275...)
Affinity DataIC50: 5.92E+5nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330396(1-((3-(l-Prolinol)-1-yl)-propyl)uracil | CHEMBL127...)
Affinity DataIC50: 7.12E+5nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330391(5-(3-(benzyloxy)benzyl)-1-((2-hydroxyethoxy)methyl...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330393(5-benzylpyrimidine-2,4,6(1H,3H,5H)-trione | CHEMBL...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50078082(5-(3-Benzyloxy-benzyl)-pyrimidine-2,4,6-trione | C...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed