Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50032368
LigandPNGBDBM50327907(trans-2-amino-8-(4-hydroxycyclohexyl)-4-methyl-6-(...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of AKT in human BT20 cells assessed as inhibition of S473 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50327903(trans-2-amino-8-(4-(2-hydroxyethoxy)cyclohexyl)-4-...)
Affinity DataIC50: 5.74nMAssay Description:Inhibition of AKT in human BT20 cells assessed as inhibition of S473 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50327905(trans-2-amino-8-((1r,4r)-4-hydroxycyclohexyl)-6-(6...)
Affinity DataIC50: 14.3nMAssay Description:Inhibition of AKT in human BT20 cells assessed as inhibition of S473 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50327906(2-amino-4-methyl-6-(6-methylpyridin-3-yl)-8-(tetra...)
Affinity DataIC50: 25nMAssay Description:Inhibition of AKT in human BT20 cells assessed as inhibition of S473 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50327904(2-amino-4-methyl-6-(1H-pyrazol-3-yl)-8-(tetrahydro...)
Affinity DataIC50: 68nMAssay Description:Inhibition of AKT in human BT20 cells assessed as inhibition of S473 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327904(2-amino-4-methyl-6-(1H-pyrazol-3-yl)-8-(tetrahydro...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327907(trans-2-amino-8-(4-hydroxycyclohexyl)-4-methyl-6-(...)
Affinity DataKi:  0.850nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327906(2-amino-4-methyl-6-(6-methylpyridin-3-yl)-8-(tetra...)
Affinity DataKi:  5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327894(US8633204, 209 | CHEMBL1258458 | 2-amino-8-isoprop...)
Affinity DataKi:  5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327903(trans-2-amino-8-(4-(2-hydroxyethoxy)cyclohexyl)-4-...)
Affinity DataKi:  5.11nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327897(2-amino-8-isopropyl-4-methyl-6-(1H-pyrazol-5-yl)pt...)
Affinity DataKi:  6nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327905(trans-2-amino-8-((1r,4r)-4-hydroxycyclohexyl)-6-(6...)
Affinity DataKi:  6.80nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327896(2-amino-4-methyl-8-(1-methylethyl)-6-(1H-pyrazol-4...)
Affinity DataKi:  9nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327901(2-amino-8-isopropyl-6-(2-methoxypyrimidin-5-yl)-4-...)
Affinity DataKi:  18nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327900(2-amino-8-isopropyl-6-(6-methoxypyridin-3-yl)-4-me...)
Affinity DataKi:  30nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327898(2-amino-8-isopropyl-4-methyl-6-(1H-1,2,3-triazol-5...)
Affinity DataKi:  113nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327902(2-amino-8-isopropyl-6-(2-methoxypyridin-4-yl)-4-me...)
Affinity DataKi:  947nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327899(2-amino-8-isopropyl-6-(2-methoxypyridin-3-yl)-4-me...)
Affinity DataKi:  3.94E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327895(2-amino-8-isopropyl-4-methoxy-6-(6-methoxypyridin-...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed