Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50032924
TargetNeutrophil elastase(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50326056((1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazin...)
Affinity DataIC50: 680nMAssay Description:Inhibition of human leukocyte elastase after 60 mins fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCathepsin B(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50326056((1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazin...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human CatB after 60 mins fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Rat)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50336545((1R,2S)-1-((2S,4R)-4-(8-bromo-2-(2-isobutyramidoth...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of rat hapatic, acyl coA cholesterol acetyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCathepsin B(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM12311(SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human CatB after 60 mins fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 2B catalytic subunit beta isoform(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50336545((1R,2S)-1-((2S,4R)-4-(8-bromo-2-(2-isobutyramidoth...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human PP2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM12311(SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human leukocyte elastase after 60 mins fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCathepsin B(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50336545((1R,2S)-1-((2S,4R)-4-(8-bromo-2-(2-isobutyramidoth...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human CatB after 60 mins fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCathepsin E(Mouse)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50336545((1R,2S)-1-((2S,4R)-4-(8-bromo-2-(2-isobutyramidoth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mouse recombinant cathepsin E by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50336545((1R,2S)-1-((2S,4R)-4-(8-bromo-2-(2-isobutyramidoth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human leukocyte elastase after 60 mins fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed