Compile Data Set for Download or QSAR
Report error Found 68 Enz. Inhib. hit(s) with all data for entry = 50032427
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329079(N2-(2,6-dimorpholinopyridin-4-yl)-N4-(1H-indazol-4...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329070(N2-(3,5-dimorpholinophenyl)-N4-(1H-indazol-4-yl)-N...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329080(N2-(2,6-dimorpholinopyrimidin-4-yl)-N4-(1H-indazol...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293247(N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N2-(3,5-dimo...)
Affinity DataIC50: 4nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329079(N2-(2,6-dimorpholinopyridin-4-yl)-N4-(1H-indazol-4...)
Affinity DataIC50: 5nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329070(N2-(3,5-dimorpholinophenyl)-N4-(1H-indazol-4-yl)-N...)
Affinity DataIC50: 9nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329065(N2-(3,5-dimorpholinophenyl)-N4-(1H-indazol-4-yl)py...)
Affinity DataIC50: 11nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329076(N-(3-(4-((1H-indazol-4-yl)(methyl)amino)pyrimidin-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293247(N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N2-(3,5-dimo...)
Affinity DataIC50: 14nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329072((3-(4-((1H-indazol-4-yl)(methyl)amino)pyrimidin-2-...)
Affinity DataIC50: 21nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329080(N2-(2,6-dimorpholinopyrimidin-4-yl)-N4-(1H-indazol...)
Affinity DataIC50: 24nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM25226(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(3-meth...)
Affinity DataIC50: 25nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329074(3-(4-((1H-indazol-4-yl)(methyl)amino)pyrimidin-2-y...)
Affinity DataIC50: 29nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329053(N4-(benzo[d][1,3]dioxol-4-yl)-N2-(3-(methylsulfony...)
Affinity DataIC50: 34nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329061(N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N4-methyl-N2...)
Affinity DataIC50: 36nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329069(N4-(1H-indazol-4-yl)-N4-methyl-N2-(3-(methylsulfon...)
Affinity DataIC50: 36nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329061(N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N4-methyl-N2...)
Affinity DataIC50: 42nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329069(N4-(1H-indazol-4-yl)-N4-methyl-N2-(3-(methylsulfon...)
Affinity DataIC50: 51nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329078(N4-(3-chloro-1H-indazol-4-yl)-N2-(3,5-dimorpholino...)
Affinity DataIC50: 55nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329070(N2-(3,5-dimorpholinophenyl)-N4-(1H-indazol-4-yl)-N...)
Affinity DataIC50: 58nMAssay Description:Inhibition of PDGFRbeta phosphorylation in human MG63 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329059(N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)...)
Affinity DataIC50: 61nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329077(N2-(3,5-dimorpholinophenyl)-N4-(3-methyl-1H-indazo...)
Affinity DataIC50: 67nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329075(N-(3-(4-(1H-indazol-4-ylamino)pyrimidin-2-ylamino)...)
Affinity DataIC50: 84nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329066(N2-(3,5-dimorpholinophenyl)-N4-(1H-indazol-7-yl)py...)
Affinity DataIC50: 89nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329062(2-((5-chlorobenzo[d][1,3]dioxol-4-yl)(2-(3-(methyl...)
Affinity DataIC50: 95nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329068(N4-(1H-benzo[d][1,2,3]triazol-4-yl)-N2-(3,5-dimorp...)
Affinity DataIC50: 115nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329067(N2-(3,5-dimorpholinophenyl)-N4-(1H-indol-4-yl)pyri...)
Affinity DataIC50: 117nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329064(2-((5-chlorobenzo[d][1,3]dioxol-4-yl)(2-(3-(methyl...)
Affinity DataIC50: 121nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329053(N4-(benzo[d][1,3]dioxol-4-yl)-N2-(3-(methylsulfony...)
Affinity DataIC50: 186nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329064(2-((5-chlorobenzo[d][1,3]dioxol-4-yl)(2-(3-(methyl...)
Affinity DataIC50: 187nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM25226(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(3-meth...)
Affinity DataIC50: 187nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329062(2-((5-chlorobenzo[d][1,3]dioxol-4-yl)(2-(3-(methyl...)
Affinity DataIC50: 190nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329071((3-(4-(1H-indazol-4-ylamino)pyrimidin-2-ylamino)ph...)
Affinity DataIC50: 204nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329055(N4-(benzofuran-7-yl)-N2-(3-(methylsulfonyl)phenyl)...)
Affinity DataIC50: 205nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329057(N4-(benzo[d]oxazol-7-yl)-N2-(3-(methylsulfonyl)phe...)
Affinity DataIC50: 219nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329078(N4-(3-chloro-1H-indazol-4-yl)-N2-(3,5-dimorpholino...)
Affinity DataIC50: 227nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329072((3-(4-((1H-indazol-4-yl)(methyl)amino)pyrimidin-2-...)
Affinity DataIC50: 232nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329070(N2-(3,5-dimorpholinophenyl)-N4-(1H-indazol-4-yl)-N...)
Affinity DataIC50: 240nMAssay Description:Inhibition of KDR phosphorylation in HUVECMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329073(3-(4-(1H-indazol-4-ylamino)pyrimidin-2-ylamino)-N,...)
Affinity DataIC50: 246nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329063(N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N4-(2-methox...)
Affinity DataIC50: 246nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329054(N4-(6-chlorobenzofuran-7-yl)-N2-(3-(methylsulfonyl...)
Affinity DataIC50: 300nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329065(N2-(3,5-dimorpholinophenyl)-N4-(1H-indazol-4-yl)py...)
Affinity DataIC50: 302nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329063(N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N4-(2-methox...)
Affinity DataIC50: 378nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329081(N2-(4,6-dimorpholinopyrimidin-2-yl)-N4-(1H-indazol...)
Affinity DataIC50: 432nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329074(3-(4-((1H-indazol-4-yl)(methyl)amino)pyrimidin-2-y...)
Affinity DataIC50: 453nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329055(N4-(benzofuran-7-yl)-N2-(3-(methylsulfonyl)phenyl)...)
Affinity DataIC50: 460nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329077(N2-(3,5-dimorpholinophenyl)-N4-(3-methyl-1H-indazo...)
Affinity DataIC50: 513nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329058(N4-(benzo[d]oxazol-4-yl)-N2-(3-(methylsulfonyl)phe...)
Affinity DataIC50: 549nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329067(N2-(3,5-dimorpholinophenyl)-N4-(1H-indol-4-yl)pyri...)
Affinity DataIC50: 856nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329054(N4-(6-chlorobenzofuran-7-yl)-N2-(3-(methylsulfonyl...)
Affinity DataIC50: 897nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
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