Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 8129
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 60nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 75nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; B lb l et al., J. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 100nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 130nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 137nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; B lb l et al., J. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 140nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 150nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 150nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 157nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; B lb l et al., J. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 320nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM13075(2000-01951 | 2,4-dichloro-5-sulfamoylbenzoic acid ...)
Affinity DataIC50: 400nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM13075(2000-01951 | 2,4-dichloro-5-sulfamoylbenzoic acid ...)
Affinity DataIC50: 450nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 800nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM50308986(pyridin-2-ylmethanaminium 2,4-dichloro-5-sulfamoyl...)
Affinity DataIC50: 990nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; B lb l et al., J. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 2.80E+3nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM13075(2000-01951 | 2,4-dichloro-5-sulfamoylbenzoic acid ...)
Affinity DataIC50: 3.20E+3nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 3.60E+3nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 3.80E+3nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; B lb l et al., J. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 4.50E+3nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 5.20E+3nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; B lb l et al., J. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 6.10E+3nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM13075(2000-01951 | 2,4-dichloro-5-sulfamoylbenzoic acid ...)
Affinity DataIC50: 7.70E+3nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; B lb l et al., J. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM13075(2000-01951 | 2,4-dichloro-5-sulfamoylbenzoic acid ...)
Affinity DataIC50: 1.80E+4nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM13075(2000-01951 | 2,4-dichloro-5-sulfamoylbenzoic acid ...)
Affinity DataIC50: 2.30E+4nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; B lb l et al., J. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)