Compile Data Set for Download or QSAR
Report error Found 127 Enz. Inhib. hit(s) with all data for entry = 50032526
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330507(5-(4-Methylpiperazin-1-yl)-3-(m-tolylsulfonyl)-1H-...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330538(3-(3-Chlorophenylsulfonyl)-5-(4-methylpiperazin-1-...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330512(3-(Naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330505(3-(3-Methoxyphenylsulfonyl)-5-(4-methylpiperazin-1...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330523(1-isobutyl-5-(4-methylpiperazin-1-yl)-3-(naphthale...)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330523(1-isobutyl-5-(4-methylpiperazin-1-yl)-3-(naphthale...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330516(1-methyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330511(5-(4-Methylpiperazin-1-yl)-3-(1-naphthalenesulfony...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330516(1-methyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330517(1-ethyl-5-(4-methylpiperazin-1-yl)-3-(naphthalen-1...)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330535(3-(3-Fluorophenylsulfonyl)-5-(4-methylpiperazin-1-...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330515(1-methyl-5-(4-methylpiperazin-1-yl)-3-(naphthalen-...)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330515(1-methyl-5-(4-methylpiperazin-1-yl)-3-(naphthalen-...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330517(1-ethyl-5-(4-methylpiperazin-1-yl)-3-(naphthalen-1...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330521(1-isopropyl-5-(4-methylpiperazin-1-yl)-3-(naphthal...)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330519(5-(4-methylpiperazin-1-yl)-3-(naphthalen-1-ylsulfo...)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330519(5-(4-methylpiperazin-1-yl)-3-(naphthalen-1-ylsulfo...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330521(1-isopropyl-5-(4-methylpiperazin-1-yl)-3-(naphthal...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330533(5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-i...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330518(1-ethyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1...)
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330518(1-ethyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330525(1-benzyl-5-(4-methylpiperazin-1-yl)-3-(naphthalen-...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330525(1-benzyl-5-(4-methylpiperazin-1-yl)-3-(naphthalen-...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330520(3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1-p...)
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330520(3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1-p...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330510(3-(2,6-Dichlorophenylsulfonyl)-5-(4-methylpiperazi...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330522(1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperaz...)
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330514(1-ethyl-3-(phenylsulfonyl)-5-(piperazin-1-yl)-1H-i...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330514(1-ethyl-3-(phenylsulfonyl)-5-(piperazin-1-yl)-1H-i...)
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330522(1-isopropyl-3-(naphthalen-1-ylsulfonyl)-5-(piperaz...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330527(1-methyl-3-(phenylsulfonyl)-5-(piperazin-1-yl)-1H-...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330527(1-methyl-3-(phenylsulfonyl)-5-(piperazin-1-yl)-1H-...)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330537(3-(2-Chlorophenylsulfonyl)-5-(4-methylpiperazin-1-...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330513(7-(4-methylpiperazin-1-yl)-3-(naphthalen-1-ylsulfo...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330524(1-isobutyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazi...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330524(1-isobutyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazi...)
Affinity DataIC50: 4.60nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330508(5-(4-Methylpiperazin-1-yl)-3-tosyl-1H-indazole | C...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330536(3-(4-Fluorophenylsulfonyl)-5-(4-methylpiperazin-1-...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330534(3-(2-fluorophenylsulfonyl)-5-(4-methylpiperazin-1-...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330526(1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330526(1-benzyl-3-(naphthalen-1-ylsulfonyl)-5-(piperazin-...)
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330509(5-(4-Methylpiperazin-1-yl)-3-(thiophen-2-ylsulfony...)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330511(5-(4-Methylpiperazin-1-yl)-3-(1-naphthalenesulfony...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330539(3-(4-Chlorophenylsulfonyl)-5-(4-methylpiperazin-1-...)
Affinity DataKi:  8.10nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330533(5-(4-methylpiperazin-1-yl)-3-(phenylsulfonyl)-1H-i...)
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330540(3-(3-fluorophenylsulfonyl)-6-(piperazin-1-yl)-1H-i...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330506(3-(4-Methoxyphenylsulfonyl)-5-(4-methylpiperazin-1...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330512(3-(Naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330513(7-(4-methylpiperazin-1-yl)-3-(naphthalen-1-ylsulfo...)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330545(3-(naphthalen-1-ylsulfonyl)-6-(piperazin-1-yl)-1H-...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
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