Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50032565
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human IMPDH2 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054017(6-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydroisobenz...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054017(6-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydroisobenz...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human IMPDH2 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50228085(N-hydroxy-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50228085(N-hydroxy-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human IMPDH2 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331099(7-Hydroxy-6-((E)-6-hydroxy-3-methyl-hex-2-enyl)-5-...)
Affinity DataIC50: 770nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331099(7-Hydroxy-6-((E)-6-hydroxy-3-methyl-hex-2-enyl)-5-...)
Affinity DataIC50: 790nMAssay Description:Inhibition of human IMPDH2 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331100(methyl 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-d...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human IMPDH2 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331100(methyl 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-d...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331098(6-(4-acetoxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroi...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human IMPDH2 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331098(6-(4-acetoxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroi...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331101(6-(4,6-dimethoxy-7-methyl-3-oxo-1,3-dihydroisobenz...)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331101(6-(4,6-dimethoxy-7-methyl-3-oxo-1,3-dihydroisobenz...)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of human IMPDH2 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed