Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50032567
TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-Lys(TFAc)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331108((S)-2-(4-(dimethylamino)benzamido)-N8-hydroxy-N1-(...)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-Lys(TFAc)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331106((S)-tert-butyl 1-(cyclopentylamino)-8-(hydroxyamin...)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261816(tert-butyl 4-(3-((7-(hydroxyamino)-7-oxoheptyl)car...)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-RHKK(Ac)-ACC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331106((S)-tert-butyl 1-(cyclopentylamino)-8-(hydroxyamin...)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-RHKK(Ac)-ACC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261816(tert-butyl 4-(3-((7-(hydroxyamino)-7-oxoheptyl)car...)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331109(CHEMBL1290142 | US8748451, 1 | 6-(9H-carbazol-9-yl...)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-RHKK(Ac)-ACC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-Lys(TFAc)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331107((S)-N-(8-(hydroxyamino)-1,8-dioxo-1-(quinolin-8-yl...)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-Lys(TFAc)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 76nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-Lys(TFAc)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331107((S)-N-(8-(hydroxyamino)-1,8-dioxo-1-(quinolin-8-yl...)
Affinity DataIC50: 107nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331105((S)-tert-butyl 1-(cyclopentylamino)-7-hydroxy-1-ox...)
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261816(tert-butyl 4-(3-((7-(hydroxyamino)-7-oxoheptyl)car...)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-Lys(TFAc)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331108((S)-2-(4-(dimethylamino)benzamido)-N8-hydroxy-N1-(...)
Affinity DataIC50: 943nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331106((S)-tert-butyl 1-(cyclopentylamino)-8-(hydroxyamin...)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-Lys(TFAc)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-Lys(TFAc)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331106((S)-tert-butyl 1-(cyclopentylamino)-8-(hydroxyamin...)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-RHKK(Ac)-ACC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331109(CHEMBL1290142 | US8748451, 1 | 6-(9H-carbazol-9-yl...)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-RHKK(Ac)-ACC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261816(tert-butyl 4-(3-((7-(hydroxyamino)-7-oxoheptyl)car...)
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-RHKK(Ac)-ACC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331105((S)-tert-butyl 1-(cyclopentylamino)-7-hydroxy-1-ox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-Lys(TFAc)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed